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Kaoru Kiguchi

Explore the profile of Kaoru Kiguchi including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 1642
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Recent Articles
1.
Sandoval M, Sloat B, Lansakara-P D, Kumar A, Rodriguez B, Kiguchi K, et al.
J Control Release . 2024 Dec; 378:1154. PMID: 39721821
No abstract available.
2.
Saha A, Blando J, Fernandez I, Kiguchi K, DiGiovanni J
Oncotarget . 2016 Feb; 7(18):25194-207. PMID: 26910370
A cell line was established from ventral prostate (VP) tumors of one-year-old Hi-Myc mice. These cells, called HMVP2 cells, are LinnegSca-1highCD49fhigh with high CD44 and CD29 expression and express CK14,...
3.
Kitamura T, Srivastava J, DiGiovanni J, Kiguchi K
Mol Carcinog . 2014 May; 54(6):459-72. PMID: 24839254
Although very few studies have addressed the molecular and cellular mechanisms underlying the development of biliary tract cancer (BTC), several lines of evidence suggest a role for the erbB receptor...
4.
Macias E, Rao D, Carbajal S, Kiguchi K, DiGiovanni J
J Invest Dermatol . 2014 Feb; 134(7):1971-1980. PMID: 24496235
The nuclear transcription factor signal transducer and activator of transcription 3 (Stat3) has recently been reported to have a localized mitochondrial regulatory function. Current data suggest that mitochondrial Stat3 (mitoStat3)...
5.
Kiguchi K
J Hepatobiliary Pancreat Sci . 2014 Jan; 21(6):371-9. PMID: 24420749
Novel targets for therapeutic or chemopreventive approaches against cholangiocarcinoma (CCA) are urgently needed. In this review article, we discuss the molecular aspects of CCA including the role of erbB receptor...
6.
Rho O, Kiguchi K, Jiang G, DiGiovanni J
Mol Carcinog . 2013 Oct; 53(11):871-82. PMID: 24114993
In this study, we examined the impact of rapamycin on mTORC1 signaling during 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced keratinocyte proliferation and skin tumor promotion in both wild-type (FVB/N) and BK5.Akt(WT) mice. TPA activated...
7.
Rao D, Macias E, Carbajal S, Kiguchi K, DiGiovanni J
Mol Carcinog . 2013 Sep; 54(2):121-33. PMID: 24038534
STATs play crucial roles in a wide variety of biological functions, including development, proliferation, differentiation and migration as well as in cancer development. In the present study, we examined the...
8.
Wonganan P, Chung W, Zhu S, Kiguchi K, DiGiovanni J, Cui Z
Cancer Biol Ther . 2012 Jul; 13(10):908-14. PMID: 22785206
Gemcitabine is a deoxycytidine analog used for the treatment of a wide range of solid tumors. Its efficacy is however often reduced due to the development of resistance. Ribonucleotide reductase...
9.
Shen J, Abel E, Riggs P, Repass J, Hensley S, Schroeder L, et al.
Carcinogenesis . 2012 Jul; 33(11):2208-19. PMID: 22782996
Genetic susceptibility to two-stage skin carcinogenesis is known to vary significantly among different stocks and strains of mice. In an effort to identify specific protein changes or altered signaling pathways...
10.
Kitamura T, Connolly K, Ruffino L, Ajiki T, Lueckgen A, DiGiovanni J, et al.
J Hepatol . 2012 Feb; 57(1):84-91. PMID: 22326466
Background & Aims: Gallbladder carcinoma (GBCa), a type of biliary tract cancer (BTC), has proven challenging to treat, demonstrating the need for more effective therapeutic strategies. In our current study,...