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Kai-Cheng Chuang

Explore the profile of Kai-Cheng Chuang including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 86
Followers 0
Related Specialties
General Medicine
Biophysics
Biology
Top 10 Co-Authors
Chuan-Mu Chen
Jeng-Jer Shieh
Shi-Wei Huang
Yi-Ju Chen
Shu-Hao Chang
Chih-Ching Yen
Jun-Kai Kao
Sin-Ting Wang
Wei Chen
Zheng-Yi Li
Published In
J Invest Dermatol
J Appl Clin Med Phys
Oncol Lett
J Clin Med
Front Aging Neurosci
Affiliations
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Recent Articles
11.
Single isocenter SRS using CAVMAT offers improved robustness to commissioning and treatment delivery uncertainty compared to VMAT
Cullom E, Xia Y, Chuang K, Gude Z, Zlateva Y, Adamson J, et al.
J Appl Clin Med Phys . 2021 Jun; 22(7):36-43. PMID: 34165217
Purpose: In this study, we evaluate and compare single isocenter multiple target VMAT (SIMT) and Conformal Arc Informed VMAT (CAVMAT) radiosurgery's sensitivity to uncertainties in dosimetric leaf gap (DLG) and...
12.
On the use of trajectory log files for machine & patient specific QA
Chuang K, Giles W, Adamson J
Biomed Phys Eng Express . 2021 May; 7(1). PMID: 34037535
Trajectory log files are increasingly being utilized clinically for machine and patient specific QA. The process of converting the DICOM-RT plan to a deliverable trajectory by the linac control software...
13.
Imiquimod Accelerated Antitumor Response by Targeting Lysosome Adaptation in Skin Cancer Cells
Chang S, Wu C, Chuang K, Huang S, Li Z, Wang S, et al.
J Invest Dermatol . 2021 Mar; 141(9):2219-2228.e8. PMID: 33744296
Lysosomal adaptation is a cellular physiological process in which the number and function of lysosomes are regulated at the transcriptional and post-transcriptional levels in response to extracellular and/or intracellular cues...
14.
EGR-1 plays a protective role in AMPK inhibitor compound C-induced apoptosis through ROS-induced ERK activation in skin cancer cells
Chuang K, Chen F, Tsai M, Shieh J
Oncol Lett . 2021 Mar; 21(4):304. PMID: 33732380
Skin cancer is caused by abnormal proliferation, gene regulation and mutation of epidermis cells. Compound C is commonly used as an inhibitor of AMP-activated protein kinase (AMPK), which serves as...
15.
A tool for patient-specific prediction of delivery discrepancies in machine parameters using trajectory log files
Chuang K, Giles W, Adamson J
Med Phys . 2020 Dec; 48(3):978-990. PMID: 33332618
Purpose: Multileaf collimator (MLC) delivery discrepancy between planned and actual (delivered) positions have detrimental effect on the accuracy of dose distributions for both IMRT and VMAT. In this study, we...
16.
Imiquimod-induced ROS production disrupts the balance of mitochondrial dynamics and increases mitophagy in skin cancer cells
Chuang K, Chang C, Chang S, Huang S, Chuang S, Li Z, et al.
J Dermatol Sci . 2020 May; 98(3):152-162. PMID: 32376151
Background: Mitochondrial homeostasis is a highly dynamic process involving continuous fission and fusion cycles and mitophagy to maintain mitochondrial functionality. Imiquimod (IMQ), a Toll-like receptor (TLR) 7 ligand, is used...
17.
Imiquimod Exerts Antitumor Effects by Inducing Immunogenic Cell Death and Is Enhanced by the Glycolytic Inhibitor 2-Deoxyglucose
Huang S, Wang S, Chang S, Chuang K, Wang H, Kao J, et al.
J Invest Dermatol . 2020 Feb; 140(9):1771-1783.e6. PMID: 32035924
The induction of immunogenic cell death (ICD) in cancer cells triggers specific immune responses against the same cancer cells. Imiquimod (IMQ) is a synthetic ligand of toll-like receptor 7 that...