Jeng-Jer Shieh
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Explore the profile of Jeng-Jer Shieh including associated specialties, affiliations and a list of published articles.
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59
Citations
6922
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Recent Articles
1.
Chung M, Lin C, Chang C, Chang Y, Hsiao P, Lien C, et al.
Clin Pharmacol Ther
. 2025 Mar;
PMID: 40059622
The benefits of sodium-glucose transport protein 2 inhibitor (SGLT2i) use on severe urolithiasis requiring surgery remains unclear. All patients with incident T2D in Taiwan National Health Institution databases (2016-2021) and...
2.
Chang S, Chuang K, Li Z, Chang M, Liu K, Hsu C, et al.
Cancers (Basel)
. 2024 Sep;
16(17).
PMID: 39272918
Mitochondria, vital organelles that generate ATP, determine cell fate. Dysfunctional and damaged mitochondria are fragmented and removed through mitophagy, a mitochondrial quality control mechanism. The FDA-approved drug IMQ, a synthetic...
3.
Chen Y, Ho H, Tseng C, Chen Y, Wang S, Shieh J, et al.
Sci Rep
. 2024 Jul;
14(1):17495.
PMID: 39079980
Short-chain fatty acids (SCFAs) have been proposed to have anti-inflammatory effects and improve immune homeostasis. We aimed to examine the effects of SCFAs on skin phenotype, systemic inflammation, and gut...
4.
Hsu C, Chang S, Yang R, Lee C, Lee M, Kao J, et al.
Environ Toxicol
. 2024 Jul;
39(11):5008-5018.
PMID: 39031462
In sepsis, bacterial components, particularly lipopolysaccharide (LPS), trigger organ injuries such as liver dysfunction. Although sepsis induces hepatocyte damage, the mechanisms underlying sepsis-related hepatic failure remain unclear. In this study,...
5.
Li Z, Chang S, Liu K, Wu A, Hsu C, Huang S, et al.
J Dermatol Sci
. 2024 Jan;
113(1):18-25.
PMID: 38185543
Background: Melanogenesis is the process of melanin maturation which not only protects skin from UV radiation but also plays an important role in antigenicity of melanomas. Imiquimod (IMQ) is a...
6.
Chung M, Hung P, Hsiao P, Wu L, Chang C, Hsiao K, et al.
JAMA Netw Open
. 2023 Feb;
6(2):e230453.
PMID: 36811856
Importance: The association between sodium-glucose transport protein 2 inhibitor (SGLT2i) use and the incidence of acute kidney injury (AKI) remains controversial. The benefits of SGLT2i use in patients to reduce...
7.
Chang S, Lin P, Wu T, Hsu C, Huang S, Li Z, et al.
J Dermatol Sci
. 2022 Sep;
107(3):142-150.
PMID: 36075780
Background: Lysosomal cell death is induced by lysosomal membrane permeabilization (LMP) and the subsequent release of lysosomal proteolytic enzymes, including cathepsins (CTSs), which results in mitochondrial dysfunction and apoptosis. Imiquimod...
8.
Chang Y, Chung M, Chang C, Chiu K, Shieh J, Wu M
Pharm Biol
. 2022 Jun;
60(1):1198-1206.
PMID: 35758295
Context: Protocatechuic aldehyde (PCA) is a natural product that has various benefits for fibrosis. Objective: This study evaluated the effects of PCA on renal fibrosis. Materials And Methods: Epithelial-mesenchymal transition...
9.
Chung M, Hsu H, Chang C, Hung P, Hsiao P, Wu L, et al.
Sci Rep
. 2022 Jun;
12(1):10147.
PMID: 35710921
Sodium-glucose cotransporter 2 inhibitor (SGLT2i) potentially decrease all-cause and cardiovascular death, however, associations with non-cardiovascular death remain unclear. Therefore, we investigated SGLT2i associations with death and the cause of death....
10.
Chung M, Hung P, Hsiao P, Wu L, Chang C, Wu M, et al.
JAMA Netw Open
. 2021 Nov;
4(11):e2135353.
PMID: 34797368
Importance: The use of sodium-glucose transport protein 2 (SGLT2) inhibitors is currently a standard intervention in patients with type 2 diabetes (T2DM) and exerts favorable pleiotropic effects to consistently lower...