Kae Shin Sim
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Explore the profile of Kae Shin Sim including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
138
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Recent Articles
1.
Tan C, Lim S, Sim K
Biochem Genet
. 2025 Jan;
PMID: 39883358
Colorectal cancer (CRC) is the third most deadly cancer diagnosed in both men and women. 5-Fluorouracil (5-FU) treatment frequently causes the CRC cells to become chemoresistance, which has a negative...
2.
Prabakaran S, Saad H, Tan C, Syed Abdul Rahman S, Sim K
Chem Biodivers
. 2024 Sep;
22(1):e202401086.
PMID: 39289837
Kaempferia parviflora or commonly known as "Kunyit hitam" by locals, is an edible plant, native to tropical regions, has been extensively utilized for culinary and medicinal applications. The present study...
3.
Ng M, Chan W, Tan M, Tan C, Tiong S, Sim K, et al.
Spectrochim Acta A Mol Biomol Spectrosc
. 2024 Sep;
325:125116.
PMID: 39276466
A new probe, 4-(((3',6'-bis(diethylamino)-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)imino)methyl)phenyl)boronic acid (R4B) was prepared by facile condensation of 4-formylphenylboronic acid and rhodamine B hydrazide. R4B was characterized by spectroscopic methods and single crystal X-ray diffraction. The...
4.
Basir N, Ramle A, Ng M, Tan C, Tiekink E, Sim K, et al.
Bioorg Chem
. 2024 Mar;
146:107256.
PMID: 38460334
A new series of indolenines decorated with pyrazolo[3,4-b]pyridines were designed and synthesized in up to 96% yield from the acid-catalyzed cyclocondensation of 1,3-dialdehydes with 3-aminopyrazoles. X-ray crystallography on a representative...
5.
Amil M, Syed Abdul Rahman S, Yap L, Abdul Razak F, Bakri M, Salem L, et al.
Chem Biodivers
. 2024 Jan;
21(3):e202301836.
PMID: 38253795
Essential oils have been recognised for their potential benefits in oral care. The aim of this study was to evaluate the antibacterial and antiproliferative activity of essential oils derived from...
6.
Ramle A, Chan N, Ng M, Tan C, Sim K, Tiekink E, et al.
Mol Divers
. 2023 Jun;
28(3):1363-1376.
PMID: 37278911
Five new compounds of benz[e]indole pyrazolyl-substituted amides (2a-e) were synthesised in low to good yields via the direct amide-coupling reaction between a pyrazolyl derivative containing a carboxylic acid and several...
7.
Sam S, Sim K, Syed Abdul Rahman S, Tan Y
Int J Med Mushrooms
. 2022 Apr;
24(3):35-50.
PMID: 35467805
Neurological diseases are increasingly recognized as a health burden worldwide, mainly affecting the elderly population. Sanguinoderma rugosum (=Amauroderma rugosum) is a wild medicinal mushroom traditionally used to alleviate inflammation and...
8.
Tan C, Sim D, Lim S, Mohidin T, Mohan G, Low Y, et al.
Planta Med
. 2022 Jan;
88(14):1325-1340.
PMID: 35100653
Two iboga-vobasine bisindoles, 16'-decarbomethoxyvoacamine (1: ) and its 19,20-dihydro derivative, 16'-decarbomethoxydihydrovoacamine (2: ) from exhibited potent cytotoxicity against the human colorectal adenocarcinoma HT-29 cells in our previous studies. Bisindoles 1:...
9.
Chan W, Saad H, Sim K, Lee V, Ang C, Yeong K, et al.
Spectrochim Acta A Mol Biomol Spectrosc
. 2021 Jul;
262:120099.
PMID: 34198119
A new chemosensor 1 was synthesized by reacting rhodamine B hydrazide and 2,3,4-trihydroxybenzaldehyde, which was then characterized by spectroscopic techniques and single crystal X-ray crystallography. Sensor 1 has the ability...
10.
Tan C, Liew J, Navanesan S, Sim K, Tan N, Tan K
J Venom Anim Toxins Incl Trop Dis
. 2020 Aug;
26:e20200013.
PMID: 32742279
Background: The Asiatic pit vipers from the complex are medically important venomous snakes. These pit vipers are often associated with snakebite that leads to fatal coagulopathy and tissue necrosis. The...