Kadri Toome
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Explore the profile of Kadri Toome including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
98
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Recent Articles
1.
Roht L, Laidre P, Tooming M, Tonisson N, Noukas M, Nurm M, et al.
Cancers (Basel)
. 2023 Jul;
15(14).
PMID: 37509324
Background: Lynch syndrome (LS) is the most frequent genetically pre-disposed colorectal cancer (CRC) syndrome, accounting for 2-3% of all CRC cases. In Estonia, ~1000 new cases are diagnosed each year....
2.
Roht L, Tooming M, Rekker K, Roomere H, Toome K, Murumets U, et al.
Front Genet
. 2022 Nov;
13:1020543.
PMID: 36425062
Colorectal cancer (CRC) is the third most common cancer in Estonia in both women and men. According to the Estonian National Institute for Health Development, in 2017, there were 357...
3.
Jurgens H, Roht L, Leitsalu L, Noukas M, Palover M, Nikopensius T, et al.
Front Genet
. 2022 Aug;
13:881100.
PMID: 35938029
Although hereditary breast cancer screening and management are well accepted and established in clinical settings, these efforts result in the detection of only a fraction of genetic predisposition at the...
4.
Saalik P, Lingasamy P, Toome K, Mastandrea I, Rousso-Noori L, Tobi A, et al.
J Control Release
. 2019 Jul;
308:109-118.
PMID: 31255690
Tumor-selective drug conjugates can potentially improve the prognosis for patients affected by glioblastoma (GBM) - the most common and malignant type of brain cancer with no effective cure. Here we...
5.
Mann A, Scodeller P, Hussain S, Braun G, Molder T, Toome K, et al.
Nat Commun
. 2018 Mar;
9(1):1070.
PMID: 29523838
The original version of the Supplementary Information associated with this Article inadvertently omitted Supplementary Table 1. The HTML has now been updated to include a corrected version of the Supplementary...
6.
Mann A, Scodeller P, Hussain S, Braun G, Molder T, Toome K, et al.
Nat Commun
. 2017 Nov;
8(1):1403.
PMID: 29123083
Cerebrovascular changes occur in Alzheimer's disease (AD). Using in vivo phage display, we searched for molecular markers of the neurovascular unit, including endothelial cells and astrocytes, in mouse models of...
7.
Toome K, Willmore A, Paiste P, Tobi A, Sugahara K, Kirsimae K, et al.
Nanoscale
. 2017 Jul;
9(28):10094-10100.
PMID: 28695222
Attaching affinity ligands to nanoparticles (NPs) increases selectivity for targeting cells and tissues, and can result in improved sensitivity and reduced off-target toxicity in diagnostic and therapeutic systems. The decision...
8.
Willmore A, Simon-Gracia L, Toome K, Paiste P, Kotamraju V, Molder T, et al.
Nanoscale
. 2015 Dec;
8(17):9096-101.
PMID: 26646247
Affinity targeting is used to deliver nanoparticles to cells and tissues. For efficient targeting, it is critical to consider the expression and accessibility of the relevant receptors in the target...
9.
Scheler O, Kaplinski L, Glynn B, Palta P, Parkel S, Toome K, et al.
BMC Biotechnol
. 2011 Mar;
11:17.
PMID: 21356118
Background: We present a comprehensive technological solution for bacterial diagnostics using tmRNA as a marker molecule. A robust probe design algorithm for microbial detection microarray is implemented. The probes were...
10.
Kaplinski L, Scheler O, Parkel S, Palta P, Toome K, Kurg A, et al.
BMC Biotechnol
. 2010 Apr;
10:34.
PMID: 20426847
Background: The hybridization of synthetic Streptococcus pneumoniae tmRNA on a detection microarray is slow at 34 degrees C resulting in low signal intensities. Results: We demonstrate that adding specific DNA...