K V Holmes
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Explore the profile of K V Holmes including associated specialties, affiliations and a list of published articles.
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105
Citations
4424
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Recent Articles
11.
Schickli J, Wentworth D, Zelus B, Holmes K, Sawicki S
Adv Exp Med Biol
. 1998 Oct;
440:735-41.
PMID: 9782352
Murine coronavirus MHV-A59 normally infects only murine cells in vitro and causes transmissible infection only in mice. In the 17 C1 1 line of murine cells, the receptor for MHV-A59...
12.
Godfraind C, Holmes K, Coutelier J
Adv Exp Med Biol
. 1998 Oct;
440:569-74.
PMID: 9782331
Expression of Bgp1a, a glycoprotein that serves as receptor for mouse hepatitis virus-A59 has been analyzed in various mouse tissues and correlated with the pathogenicity that this virus induces in...
13.
Tresnan D, Holmes K
Adv Exp Med Biol
. 1998 Oct;
440:69-75.
PMID: 9782266
Human coronavirus HCV-229E and porcine transmissible gastroenteritis virus (TGEV), both members of coronavirus group I, use aminopeptidase N (APN) as their cellular receptors. These viruses show marked species specificity in...
14.
Hensley L, Holmes K, Beauchemin N, Baric R
Adv Exp Med Biol
. 1998 Oct;
440:33-41.
PMID: 9782262
Molecular mechanisms regulating virus xenotropism and cross-species transmission are poorly understood. Host range mutants (MHV-H2) of mouse hepatitis virus (MHV) strains were isolated from mixed cultures containing progressively increasing concentrations...
15.
Zelus B, Wessner D, Dveksler G, Holmes K
Adv Exp Med Biol
. 1998 Oct;
440:3-9.
PMID: 9782258
The interaction of viruses with specific receptors is an important determinant of viral tissue tropism and species specificity. Our goals are to understand how mouse hepatitis virus (MHV) recognizes its...
16.
Zelus B, Wessner D, Williams R, Pensiero M, Phibbs F, DeSouza M, et al.
J Virol
. 1998 Aug;
72(9):7237-44.
PMID: 9696818
Mouse hepatitis virus receptor (MHVR) is a murine biliary glycoprotein (Bgp1(a)). Purified, soluble MHVR expressed from a recombinant vaccinia virus neutralized the infectivity of the A59 strain of mouse hepatitis...
17.
Wessner D, Shick P, Lu J, Cardellichio C, Gagneten S, Beauchemin N, et al.
J Virol
. 1998 Mar;
72(3):1941-8.
PMID: 9499047
The primary cellular receptor for mouse hepatitis virus (MHV), a murine coronavirus, is MHVR (also referred to as Bgp1a or C-CAM), a transmembrane glycoprotein with four immunoglobulin-like domains in the...
18.
Godfraind C, Havaux N, Holmes K, Coutelier J
J Neurovirol
. 1998 Feb;
3(6):428-34.
PMID: 9475114
BALB/c mice develop a neurologic demyelinating disease after inoculation of mouse hepatitis virus (MHV), strain A59, by the intracranial, but not by the intraperitoneal route. To determine the mechanisms that...
19.
Schickli J, Zelus B, Wentworth D, Sawicki S, Holmes K
J Virol
. 1997 Nov;
71(12):9499-507.
PMID: 9371612
In murine 17 Cl 1 cells persistently infected with murine coronavirus mouse hepatitis virus strain A59 (MHV-A59), expression of the virus receptor glycoprotein MHVR was markedly reduced (S. G. Sawicki,...
20.
Holmes K, Tresnan D, Zelus B
Adv Exp Med Biol
. 1997 Jan;
412:125-33.
PMID: 9192004
Expression of specific virus receptors on the surface of intestinal epithelial cells or M cells can determine whether or not a animal is susceptible to infection with an enterotropic virus....