K Tsukidate
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Explore the profile of K Tsukidate including associated specialties, affiliations and a list of published articles.
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28
Citations
139
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Recent Articles
1.
Sato G, Aoki T, Hosokawa S, Sagami F, Tsukidate K
Life Sci
. 2001 Jun;
68(24):2665-73.
PMID: 11400910
The present paper describes the role of conjugating enzymes in the development of hepatotoxicity after administration of repeated doses of a novel monoamine oxidase type-A (MAO-A) inhibitor, (5R)-3-[2-(( 1S)-3-cyano-1-hydroxypropyl)benzothiazol-6-yl]-5-methoxymethyl-2-oxazolidinone (E2011)....
2.
HAKURA A, Tsutsui Y, Sonoda J, Tsukidate K, Mikami T, Sagami F
Mutat Res
. 2001 Feb;
447(2):239-47.
PMID: 10751607
We recently demonstrated that not all organs with a high rate of induction of mutation in the lacZ transgene develop tumors in the lambdalacZ transgenic mice (MutaMouse) used for a...
3.
Sato G, ASAKURA S, HAKURA A, Kobayashi N, Tsukidate K
Mutat Res
. 2000 Dec;
472(1-2):163-9.
PMID: 11113709
The potential initiation activities of a novel monoamine oxidase type-A (MAO-A) inhibitor E2011, which induced preneoplastic foci in the rat liver, were investigated by comparing the mutagenic activity of E2011,...
4.
Sato G, Chimoto T, Aoki T, Hosokawa S, Sumigama S, Tsukidate K, et al.
J Toxicol Sci
. 1999 Sep;
24(3):165-75.
PMID: 10478331
(5R)-3-[2-((1S)-3-cyano-1-hydroxypropyl)benzothiazol-6-yl]-5- methoxymethyl-2-oxazolidinone (E2011) is a novel monoamine oxidase type-A (MAO-A) inhibitor. In order to assess toxicological profiles of E2011, doses of 0 (as controls), 30, 100 mg/kg of E2011 were...
5.
HAKURA A, Tsutsui Y, Sonoda J, Mikami T, Tsukidate K, Sagami F, et al.
Mutat Res
. 1999 May;
426(1):71-7.
PMID: 10320752
We have recently demonstrated that not all organs with high rates of mutation in the lacZ transgene develop tumors using the Muta Mouse. To better understand the role of in...
6.
Toritsuka N, Tsukidate K, Igarashi T
J Toxicol Sci
. 1999 Mar;
24(1):45-53.
PMID: 10073336
Effects of ER-40133, an inhibitor of angiotensin converting enzyme (ACE), on weight gain and sodium and potassium balance were studied in growing SD male rats. Thirty-two animals (seven weeks of...
7.
HAKURA A, Sonoda J, Tsutsui Y, Mikami T, Imade T, Shimada M, et al.
Regul Toxicol Pharmacol
. 1998 Aug;
27(3):273-9.
PMID: 9693078
The toxicity profile of benzo[a]pyrene (BP) was examined in the MutaMouse. The transgenic mouse integrated with lambda gt10 lacZ vectors is used worldwide as an experimental animal in in vivo...
8.
Tsukidate K, Yamamoto K, Snyder J, Farber J
Am J Pathol
. 1993 Sep;
143(3):918-25.
PMID: 8362985
We investigated the mechanism of lethal injury following the disruption of microtubules in cultured hepatocytes treated with vinblastine (VBL) or colchicine (COL). These agents kill hepatocytes by a process readily...
9.
Yamamoto K, Tsukidate K, Farber J
Biochem Pharmacol
. 1993 Aug;
46(3):483-91.
PMID: 8347172
The effects of the two inhibitors of poly(ADP-ribose) polymerase, 3-aminobenzamide (ABA) and benzamide (BA), on the oxidative killing of L929 mouse fibroblasts and primary cultures of rat hepatocytes were studied....
10.
Tsunoda H, Katayama S, Sakuma Y, Tanaka S, Tsukidate K, Abe S, et al.
Prostaglandins Leukot Essent Fatty Acids
. 1991 Jan;
42(1):51-6.
PMID: 1672771
6-Hydroxy-2-(4-sulfamoylbenzylamino)-4,5,7-trimethylbenzothiazo le hydrochloride (E6080), an orally active and selective 5-lipoxygenase inhibitor, dose-dependently inhibited the bronchospasm induced by antigen (ovalbumin) inhalation in sensitized conscious guinea pigs. The inhibitory effect of E6080...