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K T Cain

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Articles 43
Citations 239
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11.
Woychik R, Generoso W, Russell L, Cain K, Cacheiro N, Bultman S, et al.
Proc Natl Acad Sci U S A . 1990 Apr; 87(7):2588-92. PMID: 2320577
Molecular characterization of mutations in the mouse, particularly those involving agent-induced major structural alterations, is proving to be useful for correlating the structure and expression of individual genes with their...
12.
Rutledge J, Cain K, Kyle J, Cornett C, Cacheiro N, Witt K, et al.
Mutat Res . 1990 Apr; 229(2):161-72. PMID: 2320028
N,N'-Methylenebisacrylamide (MBA), a dimer of the monomeric acrylamide, was studied for induction of clastogenic effects in germ cells of male mice. It was found to be effective in inducing dominant-lethal...
13.
Generoso W, Cain K, Cornett C, Cacheiro N, Hughes L
Environ Mol Mutagen . 1990 Jan; 16(2):126-31. PMID: 2209562
Male mice were subjected to repeated inhalation exposures to different concentrations (165, 204, 250, or 300 ppm) of ethylene oxide (EtO) during an 8.5-week period. Transmitted clastogenic effects of these...
14.
Generoso W, Cain K, Hughes L, Foxworth L
Mutat Res . 1989 May; 226(1):61-4. PMID: 2716770
No abstract available.
15.
Katoh M, Cacheiro N, Cornett C, Cain K, Rutledge J, Generoso W
Mutat Res . 1989 Feb; 210(2):337-44. PMID: 2911260
Earlier studies in this laboratory revealed that ethylene oxide (EtO) or ethyl methanesulfonate (EMS) induced high frequencies of midgestation and late fetal deaths, and of malformations among some of the...
16.
Generoso W, Katoh M, Cain K, Hughes L, Foxworth L, Mitchell T, et al.
Mutat Res . 1989 Feb; 210(2):313-22. PMID: 2911257
The mouse egg is ovulated with its nucleus arrested at the metaphase-II stage of meiosis. Sperm entry triggers the completion of the second meiotic division. It has been speculated that...
17.
Generoso W, Rutledge J, Cain K, Hughes L, Downing D
Mutat Res . 1988 May; 199(1):175-81. PMID: 3362157
In an earlier study (Generoso et al., 1987), it was observed that the mutagen, ethylene oxide (EtO), produced remarkable increases in the incidence of developmental abnormalities and death of fetuses...
18.
Cain K, Cornett C, Cacheiro N, Hughes L, Owens J, Generoso W
Environ Mol Mutagen . 1988 Jan; 11(2):207-13. PMID: 2450017
Calcium cyclamate, an artificial sweetener, was studied for its effectiveness in inducing transmissible chromosomal aberrations in germ cells of male mice. Both the dominant-lethal and the heritable translocation tests were...
19.
Generoso W, Rutledge J, Cain K, Hughes L, Braden P
Mutat Res . 1987 Feb; 176(2):269-74. PMID: 3807937
When previously mated female mice were exposed to inhaled ethylene oxide at the time of fertilization of their eggs or during early pronuclear stage of the zygote (before DNA synthesis),...
20.
Shelby M, Cain K, Cornett C, Generoso W
Environ Mutagen . 1987 Jan; 9(4):363-8. PMID: 3582296
Acrylamide (AA), known to induce dominant lethals in male rodents, was studied in the mouse heritable translocation test by using intraperitoneal injections on 5 consecutive days. Matings on days 7-10...