K Sreedhara Ranganath Pai
Overview
Explore the profile of K Sreedhara Ranganath Pai including associated specialties, affiliations and a list of published articles.
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34
Citations
122
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Recent Articles
1.
Easwaran V, Pai K, Pai K
Cancers (Basel)
. 2025 Mar;
17(5).
PMID: 40075675
Mesenchymal stem cells (MSCs) are specialized cells that can differentiate into various types of cells. MSCs can be utilized to treat cancer. However, a MSC is considered a double-edged sword,...
2.
Kumar B, Kabekkodu S, Pai K
Mol Divers
. 2025 Feb;
PMID: 40009150
AKT1, a serine/threonine kinase, is pivotal in signaling and regulating cell survival, proliferation, and metabolism. This review focuses on the structural insights and the essential features required for its active...
3.
Gujaran T, Easwaran V, Sankhe R, Bakthavatchalam P, Dsouza H, Pai K
Oncol Res
. 2025 Jan;
33(2):381-395.
PMID: 39866236
Background: To date, there is no effective cure for the highly malignant brain tumor glioblastoma (GBM). GBM is the most common, aggressive central nervous system tumor (CNS). It commonly originates...
4.
Kumar S, Kumar B, Nayak R, Pandey S, Kumar N, Pai K
Mol Divers
. 2025 Jan;
PMID: 39786519
SH2 (Src Homology 2) domains play a crucial role in phosphotyrosine-mediated signaling and have emerged as promising drug targets, particularly in cancer therapy. STAT3 (Signal Transducer and Activator of Transcription...
5.
Dwarakanath D, Nayak Y, Kulal A, Pandey S, Pai K, Gaonkar S
Sci Rep
. 2024 Dec;
14(1):31994.
PMID: 39738776
This study explores the design, synthesis, and evaluation of a novel series of isobenzofuran-based imidazo[2,1-b][1,3,4]thiadiazole derivatives, targeting their antimicrobial and anticancer properties. These compounds integrate the pharmacologically significant 1,3,4-thiadiazole and...
6.
Hanuman S, B H, Pai K, Nune M
ACS Omega
. 2024 Aug;
9(32):34314-34328.
PMID: 39157094
The uterus, a vital organ in the female reproductive system, nurtures and supports developing embryos until maturity. This study focuses on addressing uterine related problems by creating a nanofibrous scaffold...
7.
Yarlagadda D, Das S, Anand Vullendula S, Manandhar S, Dengale S, Pai K, et al.
Mol Pharm
. 2024 Jul;
21(8):3951-3966.
PMID: 39049477
In this research, we utilized molecular simulations to create co-amorphous materials (CAMs) of ceritinib (CRT) with the objective of improving its solubility and bioavailability. We identified naringin (NRG) as a...
8.
Samant C, Kale R, Pai K, Nandakumar K, Bhonde M
Biochem Biophys Res Commun
. 2024 Jul;
729:150348.
PMID: 38986260
Adaptive resistance to conventional and targeted therapies remains one of the major obstacles in the effective management of cancer. Aberrant activation of key signaling mechanisms plays a pivotal role in...
9.
Kumar S, Arwind D, B H, Pandey S, Nayak R, Vithalkar M, et al.
Transl Oncol
. 2024 Jun;
46:102023.
PMID: 38852276
Medulloblastoma is a type of brain cancer that primarily affects children. While chemotherapy has been shown to be effective in treating medulloblastoma, the development of chemotherapy resistance remains a challenge....
10.
Agarwal T, Manandhar S, B H, Famurewa A, Gurram P, Suggala R, et al.
Sci Rep
. 2024 Apr;
14(1):9897.
PMID: 38688962
Alzheimer's disease (AD) is associated with cognitive deficits and epigenetic deacetylation that can be modulated by natural products. The role of natural oxyresveratrol-β-cyclodextrin (ORV) on cognition and histone deacetylase activity...