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K Ruuth

Explore the profile of K Ruuth including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 153
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Recent Articles
1.
Guan J, Tucker E, Wan H, Chand D, Danielson L, Ruuth K, et al.
Dis Model Mech . 2016 Aug; 9(9):941-52. PMID: 27483357
The first-in-class inhibitor of ALK, c-MET and ROS1, crizotinib (Xalkori), has shown remarkable clinical efficacy in treatment of ALK-positive non-small cell lung cancer. However, in neuroblastoma, activating mutations in the...
2.
Schonherr C, Ruuth K, Kamaraj S, Wang C, Yang H, Combaret V, et al.
Oncogene . 2012 Jan; 31(50):5193-200. PMID: 22286764
Neuroblastoma is a neural crest-derived embryonal tumour of the postganglionic sympathetic nervous system and a disease with several different chromosomal gains and losses, which include MYCN-amplified neuroblastoma on chromosome 2,...
3.
Nystrom M, Ruuth K, Lundgren E, Sundstrom P
Eur J Neurol . 2007 Oct; 14(11):1302-4. PMID: 17956450
Cytokines have a central role in multiple sclerosis (MS) pathogenesis and may contribute to the aetiology of MS. A polymorphism in the IFNA17 gene with an allele carrying a pre-mature...
4.
Jakobsson B, Ruuth K
Acta Anaesthesiol Scand . 2002 Mar; 46(1):114-7. PMID: 11903084
Two patients with incapacitating symptoms from restless legs syndrome, not adequately responding to conventional treatment with dopaminergic drugs, were implanted with a pump device (Isomed) for intrathecal delivery of morphine...
5.
Ruuth K, Carlsson L, Hallberg B, Lundgren E
Biochem Biophys Res Commun . 2001 Jun; 284(3):583-6. PMID: 11396940
Signaling pathways for the antiviral and antiproliferative biological effects of type I interferons (IFN) are well established. In this report we demonstrate a novel signaling pathway for IFN-alpha, as it...
6.
Aalto M, Seppa K, Mattila P, Mustonen H, Ruuth K, Hyvarinen H, et al.
Alcohol Alcohol . 2001 May; 36(3):224-30. PMID: 11373259
The aim of this research was to evaluate the effectiveness of long-term brief intervention in routine general practice. In five primary care out-patient clinics in a Finnish town, 296 male...
7.
Kandefer-Szerszen M, Ruuth K, Lundgren E
Arch Immunol Ther Exp (Warsz) . 1997 Jan; 45(1):93-9. PMID: 9090447
Radioiodinated human recombinant interferon alpha 88 (125I-HuIFN-alpha 88) binds to high affinity receptors of IFN sensitive Daudi cells (Burkitt lymphoma cell line). Suramin, a low molecular weight (1429), polyanionic compound...
8.
Ruuth K, Lundgren E, Brodin P
J Gen Virol . 1995 Apr; 76 ( Pt 4):767-77. PMID: 9049322
The Epstein-Barr virus (EBV) latent membrane protein 1 (LMP-1) is essential for EBV-induced immortalization of human primary B cells, transforms rodent fibroblasts and induces the up-regulation of several B cell...
9.
Malmqvist M, Carlsson J, Fredriksson B, Johansson L, Matsson P, Nilsson B, et al.
J Immunol Methods . 1987 Oct; 103(1):109-19. PMID: 2443576
Monoclonal antibodies against DNA from two hybridoma cell lines were produced and characterized. One had specificity for single stranded (ss) DNA with some cross-reactivity to RNA, while the other was...