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K R Kampen

Explore the profile of K R Kampen including associated specialties, affiliations and a list of published articles. Areas
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Citations 100
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Recent Articles
1.
Girardi T, Vereecke S, Sulima S, Khan Y, Fancello L, Briggs J, et al.
Leukemia . 2017 Jul; 32(3):809-819. PMID: 28744013
Several somatic ribosome defects have recently been discovered in cancer, yet their oncogenic mechanisms remain poorly understood. Here we investigated the pathogenic role of the recurrent R98S mutation in ribosomal...
2.
Shirzad R, Shahrabi S, Ahmadzadeh A, Kampen K, Shahjahani M, Saki N
Clin Transl Oncol . 2016 Jan; 18(10):957-71. PMID: 26742939
Angiogenesis, the process of blood vessel formation, is necessary for tissue survival in normal and pathologic conditions. Increased angiogenesis in BM niche is correlated with leukemia progression and resistance to...
3.
Kampen K, Scherpen F, Garcia-Manero G, Yang H, Kaspers G, Cloos J, et al.
Mol Cancer Res . 2015 May; 13(6):982-92. PMID: 25944917
Unlabelled: Loss of ephrin receptor (EphB1) expression may associate with aggressive cancer phenotypes; however, the mechanism of action remains unclear. To gain detailed insight into EphB1 function in acute myelogenous...
4.
Kampen K, Elst A, Mahmud H, Scherpen F, Diks S, Peppelenbosch M, et al.
Leukemia . 2013 Nov; 28(3):589-99. PMID: 24240200
Single kinase-targeted cancer therapies often failed prolonged responses because cancer cells bypass through alternative routes. In this study, high-throughput kinomic and proteomic approaches enabled to identify aberrant activity profiles in...
5.
Weidenaar A, Elst A, Kampen K, Meeuwsen-de Boer T, de Jonge H, Scherpen F, et al.
Br J Cancer . 2011 Nov; 105(12):1856-63. PMID: 22045186
Background: High vascular endothelial growth factor (VEGFA) levels at the time of diagnosis confer a worse prognosis to multiple malignancies. Our aim was to investigate the role of VEGFA in...
6.
Kruizinga R, de Jonge H, Kampen K, Walenkamp A, de Bont E
Pediatr Blood Cancer . 2010 Oct; 56(2):294-7. PMID: 20981743
In AML high VEGFA protein expression correlates with poor overall and relapse-free survival (OS/RFS). To date, the relevance of the various VEGFA isoforms is unclear. We determined VEGF121, VEGF145, VEGF148,...