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K M Scully

Explore the profile of K M Scully including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 348
Followers 0
Related Specialties
Molecular Biology
Science
Veterinary Medicine
Top 10 Co-Authors
M G Rosenfeld
S J Rhodes
J Humphreys
J M Holloway
D M SIMMONS
V Lunyak
T Heinzel
P E Sawchenko
K A Kalla
M Wegner
Published In
Genes Dev
Science
Proc Natl Acad Sci U S A
J Dairy Sci
Mol Endocrinol
Affiliations
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Recent Articles
1.
The effect of fertilizer nitrogen input to grass-clover swards and calving date on the productivity of pasture-based dairy production
Scully K, Keogh B, O Brien B, Casey I, Humphreys J
J Dairy Sci . 2021 May; 104(8):8870-8884. PMID: 34024604
The objective of this systems-scale study was to investigate grazing season timeframes on pasture and milk production and on milk processability of dairy systems with compact spring-calving dairy cows grazing...
2.
Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification
Scully K, Jacobson E, Jepsen K, Lunyak V, Viadiu H, Carriere C, et al.
Science . 2000 Nov; 290(5494):1127-31. PMID: 11073444
Reciprocal gene activation and restriction during cell type differentiation from a common lineage is a hallmark of mammalian organogenesis. A key question, then, is whether a critical transcriptional activator of...
3.
Role of estrogen receptor-alpha in the anterior pituitary gland
Scully K, Gleiberman A, Lindzey J, Lubahn D, Korach K, Rosenfeld M
Mol Endocrinol . 1997 Jun; 11(6):674-81. PMID: 9171231
Targeted insertional disruption of the mouse estrogen receptor-alpha (ER alpha) gene has provided a genetic model in which to test hypotheses that estrogens exert important effects in development and homeostatic...
4.
Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain
Holloway J, Szeto D, Scully K, Glass C, Rosenfeld M
Genes Dev . 1995 Aug; 9(16):1992-2006. PMID: 7649480
Transcriptional activation of the prolactin and growth hormone genes, occurring in a cell-specific fashion, requires short-range synergistic interactions between the pituitary-specific POU domain factor Pit-1 and other transcription factors, particularly...
5.
P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1
Bach I, Rhodes S, Pearse 2nd R, Heinzel T, Gloss B, Scully K, et al.
Proc Natl Acad Sci U S A . 1995 Mar; 92(7):2720-4. PMID: 7708713
A pituitary LIM homeodomain factor, P-Lim, is expressed as Rathke's pouch forms and as specific pituitary cell phenotypes are established, suggesting functional roles throughout pituitary development. While selectively expressed in...
6.
A tissue-specific enhancer confers Pit-1-dependent morphogen inducibility and autoregulation on the pit-1 gene
Rhodes S, Chen R, DiMattia G, Scully K, Kalla K, Lin S, et al.
Genes Dev . 1993 Jun; 7(6):913-32. PMID: 8504933
Pit-1 is a tissue-specific POU domain factor obligatory for the appearance of three cell phenotypes in the anterior pituitary gland. Expression of the pit-1 gene requires the actions of a...
7.
TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins
Drolet D, Scully K, SIMMONS D, Wegner M, Chu K, Swanson L, et al.
Genes Dev . 1991 Oct; 5(10):1739-53. PMID: 1916262
We have identified and characterized a new member of the leucine zipper (bZIP) gene family of transcription factors, thyrotroph embryonic factor (TEF). Analysis of the ontogeny of TEF gene expression...