K M Ferguson
Overview
Explore the profile of K M Ferguson including associated specialties, affiliations and a list of published articles.
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40
Citations
1796
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Recent Articles
1.
Ferguson K
Biochem Soc Trans
. 2004 Oct;
32(Pt 5):742-5.
PMID: 15494003
The members of the EGFR (epidermal growth factor receptor) family of RTKs (receptor tyrosine kinases), also known as the ErbB or HER family, have been implicated in many human cancers....
2.
Lemmon M, Ferguson K
Biochem Soc Trans
. 2001 Aug;
29(Pt 4):377-84.
PMID: 11497993
More than 250 pleckstrin homology (PH) domains have been identified in the human proteome. All PH domains studied to date appear to bind phosphoinositides, most binding only weakly and non-specifically....
3.
Padma-Nathan H, McMurray J, Pullman W, Whitaker J, Saoud J, Ferguson K, et al.
Int J Impot Res
. 2001 Apr;
13(1):2-9.
PMID: 11313831
IC351 (Cialis) is a selective inhibitor of PDE5. The efficacy and safety of on-demand dosing of IC351 in men with erectile dysfunction was assessed in a multicenter, double-blind, placebo-controlled study....
4.
Ferguson K, Kavran J, Sankaran V, Fournier E, Isakoff S, Skolnik E, et al.
Mol Cell
. 2000 Sep;
6(2):373-84.
PMID: 10983984
Pleckstrin homology (PH) domains are protein modules of around 120 amino acids found in many proteins involved in cellular signaling. Certain PH domains drive signal-dependent membrane recruitment of their host...
5.
Ferguson K, Darling P, Mohan M, Macatee T, Lemmon M
EMBO J
. 2000 Sep;
19(17):4632-43.
PMID: 10970856
Many different growth factor ligands, including epidermal growth factor (EGF) and the neuregulins (NRGs), regulate members of the erbB/HER family of receptor tyrosine kinases. These growth factors induce erbB receptor...
6.
Lemmon M, Ferguson K
Biochem J
. 2000 Aug;
350 Pt 1:1-18.
PMID: 10926821
Pleckstrin homology (PH) domains are small protein modules of around 120 amino acids found in many proteins involved in cell signalling, cytoskeletal rearrangement and other processes. Although several different protein...
7.
Isakoff S, Cardozo T, ANDREEV J, Li Z, Ferguson K, Abagyan R, et al.
EMBO J
. 1998 Sep;
17(18):5374-87.
PMID: 9736615
Phosphatidylinositol 3-kinase (PI3K) mediates a variety of cellular responses by generating PtdIns(3,4)P2 and PtdIns(3,4,5)P3. These 3-phosphoinositides then function directly as second messengers to activate downstream signaling molecules by binding pleckstrin...
8.
Lemmon M, Ferguson K
Curr Top Microbiol Immunol
. 1997 Dec;
228:39-74.
PMID: 9401202
No abstract available.
9.
Lemmon M, Ferguson K, Schlessinger J
Cell
. 1996 May;
85(5):621-4.
PMID: 8646770
No abstract available.
10.
Ferguson K, Lemmon M, Schlessinger J, SIGLER P
Cell
. 1995 Dec;
83(6):1037-46.
PMID: 8521504
The X-ray crystal structure of the high affinity complex between the pleckstrin homology (PH) domain from rat phospholipase C-delta 1 (PLC-delta 1) and inositol-(1,4,5)-trisphosphate (Ins(1,4,5)P3) has been refined to 1.9...