K Jacobson
Overview
Explore the profile of K Jacobson including associated specialties, affiliations and a list of published articles.
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173
Citations
6224
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Recent Articles
1.
Dhaliwal J, Carroll M, deBruyn J, Ricciuto A, Benchimol E, Lawrence S, et al.
J Crohns Colitis
. 2021 Aug;
16(2):216-223.
PMID: 34379117
Background: Canadian-born children of South Asian [SA] ethnicity develop inflammatory bowel disease [IBD] at similar rates to those among Caucasian children. We evaluated the variation in phenotypic spectrum of IBD...
2.
Dhaliwal J, Walters T, Mack D, Huynh H, Jacobson K, Otley A, et al.
J Crohns Colitis
. 2019 May;
14(4):445-454.
PMID: 31136648
Background And Aims: Incidence of paediatric inflammatory bowel disease [IBD] in Canada is among the highest worldwide, and age of onset may be decreasing. In a multicentre nationwide inception cohort...
3.
Rashvand S, Behrooz M, Samsamikor M, Jacobson K, Hekmatdoost A
J Hum Nutr Diet
. 2018 Feb;
31(3):408-412.
PMID: 29468761
Background: Recent evidence indicates a role for dietary factors in the pathogenesis of ulcerative colitis (UC). The aim of the present study was to investigate the relationship between dietary patterns...
4.
Morampudi V, Dalwadi U, Bhinder G, Sham H, Gill S, Chan J, et al.
Mucosal Immunol
. 2016 Jan;
9(5):1218-33.
PMID: 26813339
Intestinal goblet cells are potentially key players in controlling susceptibility to ulcerative colitis (UC). Although impaired mucin (Muc2) production by goblet cells increases microbial stimulation of the colonic mucosa, goblet...
5.
Ngoh E, Brugger H, Monajemi M, Menzies S, Hirschfeld A, Del Bel K, et al.
Genes Immun
. 2015 Jul;
16(7):452-61.
PMID: 26226011
Crohn's disease (CD) is a polygenic immune-mediated disease characterized by gastrointestinal inflammation. Mice deficient in the hematopoietic-restricted SH2 domain-containing inositolpolyphosphate 5'-phosphatase (SHIP) develop spontaneous CD-like ileal inflammation. Intriguingly, SHIP mRNA...
6.
Gibson D, Gill S, Brown K, Tasnim N, Ghosh S, Innis S, et al.
Gut Microbes
. 2015 Jan;
6(1):24-32.
PMID: 25559197
Our previous studies revealed that offspring from rat dams fed fish oil (at 8% and 18% energy), developed impaired intestinal barriers sensitizing the colon to exacerbated injury later in life....
7.
Morampudi V, Conlin V, Dalwadi U, Wu X, Marshall K, Nguyen C, et al.
Am J Physiol Gastrointest Liver Physiol
. 2014 Dec;
308(5):G389-402.
PMID: 25501546
We previously showed that vasoactive intestinal peptide (VIP) protects against bacterial pathogen-induced epithelial barrier disruption and colitis, although the mechanisms remain poorly defined. The aim of the current study was...
8.
Rubinstein B, Jacobson K, Mogilner A
Multiscale Model Simul
. 2011 Sep;
3(2):413-439.
PMID: 19116671
Cell crawling is an important biological phenomenon underlying coordinated cell movement in morphogenesis, cancer, and wound healing. In recent decades the process of cell crawling has been experimentally and theoretically...
9.
Lad R, Jacobson K
Paediatr Child Health
. 2010 Jan;
6(9):644-51.
PMID: 20084136
The face of celiac disease has changed significantly over the past 50 years. With the advent of new noninvasive and more sensitive screening tools, it has become increasingly apparent that...
10.
Conlin V, Wu X, Nguyen C, Dai C, Vallance B, Buchan A, et al.
Am J Physiol Gastrointest Liver Physiol
. 2009 Aug;
297(4):G735-50.
PMID: 19661153
Attaching and effacing bacterial pathogens attach to the apical surface of epithelial cells and disrupt epithelial barrier function, increasing permeability and allowing luminal contents access to the underlying milieu. Previous...