K J Marchbank
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Explore the profile of K J Marchbank including associated specialties, affiliations and a list of published articles.
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11
Citations
127
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Recent Articles
1.
Doekhie A, Slade M, Cliff L, Weaver L, Castaing R, Paulin J, et al.
RSC Adv
. 2022 May;
10(50):29789-29796.
PMID: 35518265
Ensilication is a novel method of protein thermal stabilisation using silica. It uses a modified sol-gel process which tailor fits a protective silica shell around the solvent accessible protein surface....
2.
McMahon O, Hallam T, Patel S, Harris C, Menny A, Zelek W, et al.
Hum Mol Genet
. 2021 Mar;
30(13):1188-1199.
PMID: 33783477
Age-related macular degeneration (AMD) is a complex neurodegenerative eye disease with behavioral and genetic etiology and is the leading cause of irreversible vision loss among elderly Caucasians. Functionally significant genetic...
3.
Doekhie A, Dattani R, Chen Y, Yang Y, Smith A, Silve A, et al.
Sci Rep
. 2020 Jun;
10(1):9243.
PMID: 32513957
Our recently developed ensilication approach can physically stabilize proteins in silica without use of a pre-formed particle matrix. Stabilisation is done by tailor fitting individual proteins with a silica coat...
4.
Phillips E, Westwood J, Brocklebank V, Wong E, Tellez J, Marchbank K, et al.
J Thromb Haemost
. 2015 Nov;
14(1):175-85.
PMID: 26559391
Unlabelled: ESSENTIALS: Molecular diagnostics has improved the differentiation of acute thrombotic microangiopathys (TMAs). Atypical hemolytic uremic syndrome may have features mimicking thrombotic thrombocytopenic purpura. We identified novel complement mutations and...
5.
Blom A, Volokhina E, Fransson V, Stromberg P, Berghard L, Viktorelius M, et al.
Clin Exp Immunol
. 2014 May;
178(1):142-53.
PMID: 24853370
Complement convertases are enzymatic complexes that play a central role in sustaining and amplification of the complement cascade. Impairment of complement function leads directly or indirectly to pathological conditions, including...
6.
Brown J, Tellez J, Wilson V, Mackie I, Scully M, Tredger M, et al.
Am J Transplant
. 2012 Mar;
12(6):1632-6.
PMID: 22420623
We report here a young female who underwent a successful deceased donor liver transplant for hepatic vein thrombosis. Five years after transplantation she developed postpartum atypical hemolytic uremic syndrome (aHUS)....
7.
Johnson S, Williams J, Hakobyan S, Richards A, Perkins S, Marchbank K, et al.
Mol Immunol
. 2010 Mar;
47(7-8):1585-91.
PMID: 20304497
Atypical hemolytic uremic syndrome (aHUS) is associated with mutations in the gene CFH encoding the complement regulator factor H (CFH). We previously reported a family, in which three individuals had...
8.
Marchbank K, Watson C, Ritsema D, Holers V
J Immunol
. 2000 Aug;
165(5):2354-61.
PMID: 10946257
Complement receptor type 2 (CR2, CD21) is expressed by both human and murine B cells and has been demonstrated to play a pivotal role in the humoral immune response. We...
9.
Marchbank K, van den Berg C, Morgan B
Immunology
. 1997 Apr;
90(4):647-53.
PMID: 9176121
Non-lethal complement (C) attack on K562 cells has been shown to induce a transient resistance to lethal amounts of C. We have previously shown that incubation of K562 with phorbol...
10.
Powell M, Marchbank K, Rushmere N, van den Berg C, Morgan B
J Immunol
. 1997 Feb;
158(4):1692-702.
PMID: 9029105
We have previously described the isolation and cloning of the rat analogue of the human complement inhibitor CD59 (hCD59). Using the rat CD59 (rCD59) coding region as probe, we have...