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D Kavanagh

Explore the profile of D Kavanagh including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 459
Followers 0
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Recent Articles
1.
Devine M, Kavanagh D, Morris M
Ir Med J . 2024 Aug; 117(7):1002. PMID: 39186070
No abstract available.
2.
Hallam T, Sharp S, Andreadi A, Kavanagh D
Immunobiology . 2023 Jul; 228(5):152410. PMID: 37478687
Complement factor I (FI) is the nexus for classical, lectin and alternative pathway complement regulation. FI is an 88 kDa plasma protein that circulates in an inactive configuration until it...
3.
McMahon O, Hallam T, Patel S, Harris C, Menny A, Zelek W, et al.
Hum Mol Genet . 2021 Mar; 30(13):1188-1199. PMID: 33783477
Age-related macular degeneration (AMD) is a complex neurodegenerative eye disease with behavioral and genetic etiology and is the leading cause of irreversible vision loss among elderly Caucasians. Functionally significant genetic...
4.
Ugrinovic S, Firth H, Kavanagh D, Gouliouris T, Gurugama P, Baxendale H, et al.
Clin Exp Immunol . 2020 Jul; 202(3):379-383. PMID: 32640035
Primary pneumococcal peritonitis is a rare infection that has been described in women but has not been previously linked with immunodeficiency. The complement system plays a central role in immune...
5.
Murtada S, Kawamura Y, Caulk A, Ahmadzadeh H, Mikush N, Zimmerman K, et al.
J R Soc Interface . 2020 May; 17(166):20200066. PMID: 32453981
Hutchinson-Gilford progeria syndrome (HGPS) is an ultra-rare disorder with devastating sequelae resulting in early death, presently thought to stem primarily from cardiovascular events. We analyse novel longitudinal cardiovascular data from...
6.
Chu E, Vo T, Chavez M, Nagasaki A, Mertz E, Nociti F, et al.
Bone . 2020 Apr; 136:115329. PMID: 32224162
Pyrophosphate (PP) serves as a potent and physiologically important regulator of mineralization, with systemic and local concentrations determined by several key regulators, including: tissue-nonspecific alkaline phosphatase (ALPL gene; TNAP protein),...
7.
White-Gibson A, Manole C, Kearney D, Kavanagh D
Ir J Med Sci . 2017 Sep; 187(2):297-300. PMID: 28866790
Introduction: Recent implementation of the European Working Time Directive in Ireland has resulted in a change from thetraditional model of patient care to a system characterised by shift work among...
8.
Phillips E, Westwood J, Brocklebank V, Wong E, Tellez J, Marchbank K, et al.
J Thromb Haemost . 2015 Nov; 14(1):175-85. PMID: 26559391
Unlabelled: ESSENTIALS: Molecular diagnostics has improved the differentiation of acute thrombotic microangiopathys (TMAs). Atypical hemolytic uremic syndrome may have features mimicking thrombotic thrombocytopenic purpura. We identified novel complement mutations and...
9.
Sheerin N, Kavanagh D, Goodship T, Johnson S
QJM . 2015 Apr; 109(1):27-33. PMID: 25899302
Background: In 2013 NHS England commissioned the use of eculizumab for both new patients with atypical haemolytic uraemic syndrome (aHUS) and those undergoing transplantation. This national service is delivered locally...
10.
Gibbons J, Nugent E, Tierney S, Kavanagh D
Ir J Med Sci . 2015 Mar; 185(1):225-9. PMID: 25772125
Background: The implementation of the European work-time directive has created increased transitions of care during weekends as doctors adhere to a shift-work structure. This raises concerns over continuity of care...