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K Gomathi

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Articles 11
Citations 236
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Recent Articles
1.
Saranya I, Akshaya R, Gomathi K, Mohanapriya R, He Z, Partridge N, et al.
Noncoding RNA Res . 2023 Nov; 9(1):153-164. PMID: 38035043
Transforming growth factor-beta1 (TGF-β1) stimulates matrix metalloproteinase-13 (, a bone-remodeling gene) expression, and this effect requires p300-mediated Runx2 (Runt-related transcription factor 2) acetylation in osteoblasts. p300 and Runx2 are transcriptional...
2.
Thirumurugan E, Gomathi K, Swathy P, Afrin S, Karthick R
Indian Heart J . 2023 Apr; 75(3):161-168. PMID: 37080484
Aim: To assess the safety, efficiency, and device compatibility of the Second Generation Robotic System. Methods: Data on Robot-Assisted PCI (R-PCI) is frequently insufficient in India. Many articles were published...
3.
Hari Krishnan R, Sadu L, Akshaya R, Gomathi K, Saranya I, Das U, et al.
Int J Biol Macromol . 2022 Nov; 225:1152-1163. PMID: 36427609
Parathyroid hormone (PTH) regulates the expression of bone remodeling genes by enhancing the activity of Runx2 in osteoblasts. p300, a histone acetyltransferase, acetylated Runx2 to activate the expression of its...
4.
Yuvaraj D, Iyyappan J, Gnanasekaran R, Ishwarya G, Harshini R, Dhithya V, et al.
Heliyon . 2021 Sep; 7(9):e07998. PMID: 34589626
In recent years, there has been an increase in demand for bioactive techniques in the food packaging industry. Although edible packaging is popular, it has yet to be effectively implemented...
5.
Gomathi K, Akshaya N, Srinaath N, Rohini M, Selvamurugan N
Int J Biol Macromol . 2020 Dec; 170:326-335. PMID: 33373635
Bone remodeling is a complex event that maintains bone homeostasis. The epigenetic mechanism of the regulation of bone remodeling has been a major research focus over the past decades. Histone...
6.
Gomathi K, Akshaya N, Srinaath N, Moorthi A, Selvamurugan N
Life Sci . 2020 Feb; 245:117389. PMID: 32007573
Osteogenesis is the process of new bone formation where transcription factors play an important role in controlling cell proliferation and differentiation. Runt-related transcription factor 2 (Runx2), a key transcription factor,...
7.
Arul V, Gopinath D, Gomathi K, Jayakumar R
J Biomed Mater Res B Appl Biomater . 2005 Apr; 73(2):383-91. PMID: 15803494
Matrikines are small peptide fragments of extracellular matrix proteins that display potent tissue repair activities. Difficulties in achieving sustained delivery of bioactive concentration of matrikines in the affected area limits...
8.
Ahmed M, Gopinath D, Gomathi K, Sehgal P, Jayakumar R
J Biomed Mater Res B Appl Biomater . 2004 Apr; 69(2):241-8. PMID: 15116414
This study evaluated the effects of noncovalently incorporated crystallin into the collagen matrix for dermal wound-healing processes in rats. Crystallin-incorporated collagen matrix (CIC) showed better healing when compared to wounds...
9.
Gopinath D, Ahmed M, Gomathi K, Chitra K, Sehgal P, Jayakumar R
Biomaterials . 2004 Jan; 25(10):1911-7. PMID: 14738855
The wound healing process involves extensive oxidative stress to the system, which generally inhibits tissue remodeling. In the present study, an improvement in the quality of wound healing was attempted...
10.
Gomathi K, Gopinath D, Ahmed M, Jayakumar R
Biomaterials . 2003 Apr; 24(16):2767-72. PMID: 12711523
We have been developing antioxidants incorporated collagen matrix as a novel biomaterial for various biomedical applications. In this study we made use of quercetin incorporated collagenous matrix for dermal wound...