K C Petruk
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Explore the profile of K C Petruk including associated specialties, affiliations and a list of published articles.
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27
Citations
793
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Recent Articles
1.
Michelakis E, Sutendra G, Dromparis P, Webster L, Haromy A, Niven E, et al.
Sci Transl Med
. 2010 May;
2(31):31ra34.
PMID: 20463368
Solid tumors, including the aggressive primary brain cancer glioblastoma multiforme, develop resistance to cell death, in part as a result of a switch from mitochondrial oxidative phosphorylation to cytoplasmic glycolysis....
2.
Yee D, Hao C, Cheung H, Chen H, Dabbagh L, Hanson J, et al.
Clin Invest Med
. 2001 May;
24(2):76-82.
PMID: 11368149
Objective: Glioblastoma cells produce cytokines with proinflammatory or immunosuppressive properties, or both, which, in addition to altered p53 gene expression, have been shown to be associated with glioblastoma resistance to...
3.
Hao C, Beguinot F, Condorelli G, Trencia A, Van Meir E, Yong V, et al.
Cancer Res
. 2001 Feb;
61(3):1162-70.
PMID: 11221847
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) preferentially triggers apoptosis in tumor cells versus normal cells, thus providing a therapeutic potential. In this study, we examined a large panel of human...
4.
Parney I, Allen P, Petruk K
Neurosurgery
. 2000 Dec;
47(6):1430-2; discussion 1432-3.
PMID: 11126914
The first use of skull tongs for cervical spine traction is credited primarily to W.G. Crutchfield. In 1933, Crutchfield described his application of extension tongs to the calvaria of a...
5.
Gainer A, Young ATL , Parney I, Petruk K, Elliott J
J Neurooncol
. 2000 Aug;
47(1):23-30.
PMID: 10930096
We used particle-mediated gene transfer by a custom-built gene gun to transfect two well-established human glioma (D54MG and U251) and melanoma (SK mel 28 and Ed 141) cell lines, as...
6.
Parney I, Chang L, Petruk K
Neurosurgery
. 2000 May;
46(5):1169-77; discussion 1177-8.
PMID: 10807250
Objective: Human gliomas are known to be immunosuppressive. Recent reports have suggested novel strategies to overcome this immunosuppression, including immunogene therapy. We examined expression of 10 immunologically important molecules by...
7.
Parney I, Hao C, Petruk K
Neurosurgery
. 2000 Apr;
46(4):778-91; discussion 791-2.
PMID: 10764250
Objective: Despite advances in conventional therapy, the prognosis for most glioma patients remains dismal. This has prompted an intensive search for effective treatment alternatives. Immunotherapy, one such alternative, has long...
8.
Anderson G, Steinke D, Petruk K, Ashforth R, Findlay J
Neurosurgery
. 1999 Dec;
45(6):1315-20; discussion 1320-2.
PMID: 10598698
Objective: Computed tomographic angiography (CTA) is a rapid and minimally invasive method of detecting intracranial aneurysms. We wished to determine whether CTA could replace digital subtraction angiography (DSA) in the...
9.
Parney I, Petruk K
J Neurooncol
. 1999 Aug;
43(1):1-10.
PMID: 10448865
Culturing human central nervous system tumors has been difficult compared to other neoplasms. We report improved success rates for establishing short term human brain tumor cultures using a modified tissue...
10.
Parney I, Petruk K, Zhang C, Sykes D, Chang L
Hum Gene Ther
. 1997 Jun;
8(9):1073-85.
PMID: 9189765
Glioblastoma multiforme is the most common primary central nervous system neoplasm. Its dismal prognosis has led to investigation of new treatment strategies such as immunogene therapy. We transduced the human...