K C Brennan
Overview
Explore the profile of K C Brennan including associated specialties, affiliations and a list of published articles.
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Articles
57
Citations
1495
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Recent Articles
1.
Pietrobon D, Brennan K
J Headache Pain
. 2025 Jan;
26(1):17.
PMID: 39871148
A key unanswered question in migraine neurobiology concerns the mechanisms that make the brain of migraineurs susceptible to cortical spreading depression (CSD, a spreading depolarization that underlies migraine aura and...
2.
Vitale M, Tottene A, Zadeh M, Brennan K, Pietrobon D
J Headache Pain
. 2023 Dec;
24(1):171.
PMID: 38124033
No abstract available.
3.
Suryavanshi P, Sawant-Pokam P, Clair S, Brennan K
Brain
. 2023 Oct;
147(2):680-697.
PMID: 37831655
Migraine is a common and disabling neurological disorder. The headache and sensory amplifications of migraine are attributed to hyperexcitable sensory circuits, but a detailed understanding remains elusive. A mutation in...
4.
Hugger S, Do T, Ashina H, Goicochea M, Jenkins B, Sacco S, et al.
Lancet Neurol
. 2023 Sep;
22(10):934-945.
PMID: 37717587
Migraine is an evolving, and sometimes lifelong disorder. The prevalence of episodic migraine peaks among individuals aged in their late 30s, implying a tendency for the disorder to remit with...
5.
Martindale C, Presson A, Schwedt T, Brennan K, Cortez M
Headache
. 2023 Aug;
63(8):1061-1069.
PMID: 37638410
Objective: To examine whether sensory hypersensitivity contributes to headache-related disability in a secondary analysis of patients with post-traumatic headache. Background: Up to one-third of individuals with traumatic brain injuries report...
6.
Reinhart K, Morton R, Brennan K, Carlson A, Shuttleworth C
J Neurochem
. 2023 Aug;
168(5):855-867.
PMID: 37596720
Spreading depolarization (SD) has emerged as an important contributor to the enlargement of acute brain injuries. We previously showed that the N-methyl-D-aspartate receptor antagonist ketamine was able to prevent deleterious...
7.
Vitale M, Tottene A, Zadeh M, Brennan K, Pietrobon D
J Headache Pain
. 2023 Aug;
24(1):105.
PMID: 37553625
Background: There is increasing evidence from human and animal studies that cortical spreading depression (CSD) is the neurophysiological correlate of migraine aura and a trigger of migraine pain mechanisms. The...
8.
Cortez M, Martindale C, Brennan K, Kean J, Millar M, Knudson A, et al.
Headache
. 2023 May;
63(5):672-682.
PMID: 37140215
Objective: To present an updated version of the Utah Photophobia Symptom Impact Scale version 2 (UPSIS2), providing robust clinical and psychometric validation, to improve headache-specific evaluation of light sensitivity and...
9.
Do T, Hougaard A, Dussor G, Brennan K, Amin F
J Headache Pain
. 2023 Jan;
24(1):3.
PMID: 36627561
Background: Despite the pervasiveness of migraine, the underlying pathophysiological mechanisms initiating migraine attacks are far from well understood and are matter of scientific debate. Objective: In this narrative review, we...
10.
Carlson A, Davis H, Jones T, Brennan K, Torbey M, Ahmadian R, et al.
Transl Stroke Res
. 2022 May;
14(2):280.
PMID: 35585425
No abstract available.