K C Barnes
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Explore the profile of K C Barnes including associated specialties, affiliations and a list of published articles.
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47
Citations
742
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Recent Articles
1.
Mathias R, Weinberg A, Boguniewicz M, Zaccaro D, Armstrong B, Schneider L, et al.
Br J Dermatol
. 2013 Apr;
169(3):700-3.
PMID: 23600999
Background: The increased susceptibility of patients with atopic dermatitis (AD) to disseminated viral skin infections such as eczema herpeticum (ADEH+) is poorly understood. Objectives: The primary goal of the current...
2.
Figueiredo J, Oliveira R, Cardoso L, Barnes K, Grant A, Carvalho E, et al.
Parasite Immunol
. 2012 Aug;
34(12):604-10.
PMID: 22861127
Field studies have suggested an immune-mediated mechanism associated with resistance to Schistosoma mansoni infection. Overall, levels of specific IgE have been correlated with resistance to infection, whereas levels of IgG4...
3.
Palmer L, Barnes K, Burton P, Chen H, Cookson W, Deichmann K, et al.
Hum Mol Genet
. 2011 Apr;
10(8):891-99.
PMID: 21523954
Asthma is a common, complex human disease. Gene discovery in asthma has been complicated by substantial etiological heterogeneity, the possibility of genes of small effect and the concomitant requirement for...
4.
Grant A, Araujo M, Ponte E, Oliveira R, Cruz A, Barnes K, et al.
Genes Immun
. 2010 Oct;
12(1):46-50.
PMID: 20927126
Interleukin (IL)-10 is a regulatory cytokine of the helper T cell type 2 (TH2) pathway, which underlies both the host defense to helminthic infection and atopic diseases, including asthma. Although...
5.
Gao P, Grigoryev D, Rafaels N, Mu D, Wright J, Cheadle C, et al.
Clin Exp Allergy
. 2010 Jul;
40(9):1353-64.
PMID: 20618347
Background: Sensitization to cockroach allergen is one of the strongest predictors of asthma morbidity, especially among African Americans. Objective: Our aims were to determine the genomic basis of cockroach sensitization...
6.
Hunninghake G, Soto-Quiros M, Avila L, Kim H, Lasky-Su J, Rafaels N, et al.
Allergy
. 2010 Jun;
65(12):1566-75.
PMID: 20560908
Background: Single nucleotide polymorphisms (SNPs) in thymic stromal lymphopoietin (TSLP) have been associated with IgE (in girls) and asthma (in general). We sought to determine whether TSLP SNPs are associated...
7.
Vergara C, Jimenez S, Acevedo N, Martinez B, Mercado D, Gusmao L, et al.
Clin Exp Allergy
. 2009 Jul;
39(10):1558-68.
PMID: 19624525
Background: G protein-coupled receptor 154 was described as an asthma susceptibility gene by positional cloning. It has been subsequently associated with asthma and other inflammatory diseases in several populations with...
8.
Hansel N, Gao L, Rafaels N, Mathias R, Neptune E, Tankersley C, et al.
Eur Respir J
. 2009 Feb;
34(1):103-10.
PMID: 19196818
Only a fraction of all smokers develop chronic obstructive pulmonary disease (COPD), suggesting a large role for genetic susceptibility. The leptin receptor (LEPR) is present in human lung tissue and...
9.
Hansel N, Cheadle C, Diette G, Wright J, Thompson K, Barnes K, et al.
Allergy
. 2008 Feb;
63(3):366-9.
PMID: 18269679
Background: Allergic diseases are thought to involve dysregulated activation of T cells including CD4+ lymphocytes. T-cell activation results in changes in gene expression, but the optimal method to study gene...
10.
Grigoryev D, Liu M, Cheadle C, Barnes K, Rabb H
Transplant Proc
. 2006 Dec;
38(10):3333-6.
PMID: 17175265
Increased organ ischemia time leads to delayed graft function (DGF), increased acute rejection (AR), enhanced chronic allograft nephropathy (CAN), and reduced long-term allograft survival. The mechanisms by which IRI predisposes...