K C Barnes
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Explore the profile of K C Barnes including associated specialties, affiliations and a list of published articles.
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47
Citations
742
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Recent Articles
11.
Palomero T, Barnes K, Real P, Glade Bender J, Sulis M, Murty V, et al.
Leukemia
. 2006 May;
20(7):1279-87.
PMID: 16688224
Activating mutations in NOTCH1 are present in over 50% of human T-cell lymphoblastic leukemia (T-ALL) samples and inhibition of NOTCH1 signaling with gamma-secretase inhibitors (GSI) has emerged as a potential...
12.
Barnes K, Grant A, Baltadzhieva D, Zhang S, Berg T, Shao L, et al.
Genes Immun
. 2005 Dec;
7(1):27-35.
PMID: 16355111
Proinflammatory and immunoregulatory products from C3 play a major role in phagocytosis, respiratory burst, and airways inflammation. C3 is critical in adaptive immunity; studies in mice deficient in C3 demonstrate...
13.
Barnes K, Caraballo L, Munoz M, Zambelli-Weiner A, Ehrlich E, Burki M, et al.
Clin Exp Allergy
. 2004 May;
34(5):736-44.
PMID: 15144465
Background: The inflammatory functions of complement component 5 (C5) are mediated by its receptor, C5R1, which is expressed on bronchial, epithelial, vascular endothelial and smooth muscle cells. A susceptibility locus...
14.
Barnes K
Curr Opin Allergy Clin Immunol
. 2002 Apr;
1(5):383-5.
PMID: 11964716
No abstract available.
15.
Becker K, Barnes K
J Invest Dermatol
. 2001 Nov;
117(5):1325-7.
PMID: 11710954
No abstract available.
16.
Xu J, Meyers D, Ober C, Blumenthal M, Mellen B, Barnes K, et al.
Am J Hum Genet
. 2001 May;
68(6):1437-46.
PMID: 11349227
The genomewide screen to search for asthma-susceptibility loci, in the Collaborative Study on the Genetics of Asthma (CSGA), has been conducted in two stages and includes 266 families (199 nuclear...
17.
Mathias R, Freidhoff L, Blumenthal M, Meyers D, Lester L, KING R, et al.
Genet Epidemiol
. 2001 Mar;
20(3):340-55.
PMID: 11255243
Variance components models were used to analyze total IgE levels in families ascertained though the Collaborative Study of the Genetics of Asthma (CSGA) using a genome-wide array of polymorphic markers....
18.
Liang K, Hsu F, Beaty T, Barnes K
Am J Hum Genet
. 2001 Mar;
68(4):937-50.
PMID: 11254451
In the present study we propose a multipoint approach, for the mapping of genes, that is based on the case-parent trio design. We first derive an expression for the expected...
19.
Barnes K, Mathias R, Nickel R, Freidhoff L, Stockton M, Xue X, et al.
Genomics
. 2001 Feb;
71(2):246-51.
PMID: 11161818
Genetic heterogeneity has been proposed as a hallmark feature of allergic disease. To test the hypothesis that total IgE levels are jointly influenced by a locus on chromosome 12q21.1-q21.31 and...
20.
Barnes K
J Allergy Clin Immunol
. 2000 Nov;
106(5 Suppl):S192-200.
PMID: 11080731
Genetic research in allergic disease has focused primarily on asthma and its associated phenotypes (eg, total IgE), with very little attention given to the presence or absence of concomitant allergic...