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K Bruynseels

Explore the profile of K Bruynseels including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 10
Citations 447
Followers 0
Related Specialties
Pathology
General Medicine
Biochemistry
Top 10 Co-Authors
F Van Leuven
J Van Dorpe
R Loos
M Mercken
K Spittaels
C Van den Haute
I Laenen
F Vanstapel
P Van Hecke
K Vandezande
Published In
NMR Biomed
Am J Pathol
Atherosclerosis
Neuroscience
J Biol Chem
Affiliations
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Recent Articles
1.
[Reconstruction of the knee anterior cruciate ligament: single or double bundle?]
Cermak K, Baillon B, Bruynseels K, Salvia P, Feipel V, Remy P, et al.
Rev Med Brux . 2012 Mar; 32(6 Suppl):S90-6. PMID: 22458064
Anatomical and biomechanical studies have shown that the anterior cruciate ligament (ACL) consists of two distinct bundles, the anteromedial (AM) and posterolateral. Each bundle has its specific role during the...
2.
Neonatal neuronal overexpression of glycogen synthase kinase-3 beta reduces brain size in transgenic mice
Spittaels K, Van den Haute C, Van Dorpe J, Terwel D, Vandezande K, Lasrado R, et al.
Neuroscience . 2002 Aug; 113(4):797-808. PMID: 12182887
Glycogen synthase kinase-3beta (GSK-3beta) is important in neurogenesis. Here we demonstrate that the kinase influenced post-natal maturation and differentiation of neurons in vivo in transgenic mice that overexpress a constitutively...
3.
Sequencing of the coding exons of the LRP1 and LDLR genes on individual DNA samples reveals novel mutations in both genes
Van Leuven F, Thiry E, Lambrechts M, Stas L, Boon T, Bruynseels K, et al.
Atherosclerosis . 2001 Mar; 154(3):567-77. PMID: 11257257
Five coding polymorphisms in de LRP1 gene, i.e. A217V, A775P, D2080N, D2632E and G4379S were discovered by sequencing its 89 exons in three test-groups of 22 healthy individuals, 29 Alzheimer...
4.
Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord
Tesseur I, Van Dorpe J, Bruynseels K, Bronfman F, Sciot R, Van Lommel A, et al.
Am J Pathol . 2000 Nov; 157(5):1495-510. PMID: 11073810
The epsilon 4 allele of the human apolipoprotein E gene (ApoE4) constitutes an important genetic risk factor for Alzheimer's disease. Recent experimental evidence suggests that human ApoE is expressed in...
5.
Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons
Van Dorpe J, Smeijers L, Dewachter I, Nuyens D, Spittaels K, Van den Haute C, et al.
Am J Pathol . 2000 Oct; 157(4):1283-98. PMID: 11021833
Deposition of amyloid beta-peptide (Abeta) in cerebral vessel walls (cerebral amyloid angiopathy, CAA) is very frequent in Alzheimer's disease and occurs also as a sporadic disorder. Here, we describe significant...
6.
Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice
Spittaels K, Van den Haute C, Van Dorpe J, Geerts H, Mercken M, Bruynseels K, et al.
J Biol Chem . 2000 Sep; 275(52):41340-9. PMID: 11007782
Protein tau filaments in brain of patients suffering from Alzheimer's disease, frontotemporal dementia, and other tauopathies consist of protein tau that is hyperphosphorylated. The responsible kinases operating in vivo in...
7.
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein
Spittaels K, Van den Haute C, Van Dorpe J, Bruynseels K, Vandezande K, Laenen I, et al.
Am J Pathol . 1999 Dec; 155(6):2153-65. PMID: 10595944
Mutations in the human tau gene cause frontotemporal dementia and parkinsonism linked to chromosome 17. Some mutations, including mutations in intron 10, induce increased levels of the functionally normal four-repeat...
8.
Further observations on the uptake and effects of phosphonates in perfused rat liver studied by (31)P-NMR
Bruynseels K, Van Hecke P, Vanstapel F
NMR Biomed . 1999 Sep; 12(5):275-85. PMID: 10484816
We examined the route of uptake of 2-aminoethylphosphonate (NEthPo) and of phenylphosphonate (PhePo; 10 mM each) in perfused liver by (31)P-NMR. Uptake of NEthPo was concentrative. The rate of uptake...
9.
On the inhibition of hepatic glycogenolysis by fructose. A 31P-NMR study in perfused rat liver using the fructose analogue 2,5-anhydro-D-mannitol
Bruynseels K, Bergans N, Gillis N, van Dorpen F, Van Hecke P, Stalmans W, et al.
NMR Biomed . 1999 Jul; 12(3):145-56. PMID: 10414949
Inhibition of hormone-stimulated hepatic glycogenolysis by fructose (Fru) has been attributed to accumulation of the competitive inhibitor Fru1P and/or to the associated depletion of the substrate phosphate (Pi). To evaluate...
10.
Phosphonates as 31P-NMR markers of extra- and intracellular space and pH in perfused rat liver
Bruynseels K, Gillis N, Van Hecke P, Vanstapel F
NMR Biomed . 1998 Feb; 10(6):263-70. PMID: 9449129
We evaluated phosphonates (Po) as markers of the extra- and intracellular space in perfused rat liver. (i) In- and outwash behaviour of phenylphosphonate (PhePo), 3-amino-propylphosphonate (NProPo) and methyl phosphonate (MePo)...