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K B Jacobson

Explore the profile of K B Jacobson including associated specialties, affiliations and a list of published articles. Areas
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Articles 126
Citations 818
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1.
Meriaudeau F, Goudonnet J, Carver E, Parks J, Jacobson K, Warmack R, et al.
Appl Opt . 2008 Feb; 37(31):7276-88. PMID: 18301559
The photon scanning-tunneling microscope (PSTM) yields optical topographical images of samples that are thin or that are transparent at the wavelength used. A range of sample sizes can be imaged...
2.
Bolch W, Turner J, Yoshida H, Jacobson K, Hamm R, Crawford O
Radiat Environ Biophys . 1998 Dec; 37(3):157-66. PMID: 9840484
The radiation chemistry of photon-irradiated aqueous solutions of biological molecules may be considered under four distinct time regimes: physical transport (< or = 10(-15) s); prechemical conversion of H2O+, H2O*,...
3.
Arlinghaus H, Kwoka M, Jacobson K
Anal Chem . 1997 Sep; 69(18):3747-53. PMID: 9302874
Two novel DNA-sequencing methods are described that use DNA hybridization biosensor chips. These two techniques involve either labeling the free nucleic acid with enriched stable isotopes or hybridizing DNA without...
4.
Arlinghaus H, Kwoka M, Guo X, Jacobson K
Anal Chem . 1997 Apr; 69(8):1510-7. PMID: 9109351
A new DNA diagnostic and sequencing system has been developed that uses time-of-flight resonance ionization mass spectrometry (TOF-RIMS) to provide a rapid method of analyzing stable isotope-labeled oligonucleotides in form...
5.
Doktycz M, Hurst G, Habibi-Goudarzi S, McLuckey S, Tang K, Chen C, et al.
Anal Biochem . 1995 Sep; 230(2):205-14. PMID: 7503409
Recent advances in molecular biology are making it possible to diagnose genetic diseases and identify pathogens through the analysis of DNA. As clinical applications for molecular diagnosis increase, rapid, reliable...
6.
Doktycz M, Morris M, Dormady S, Beattie K, Jacobson K
J Biol Chem . 1995 Apr; 270(15):8439-45. PMID: 7721738
The use of short oligonucleotide probes is finding increased application in DNA sequencing and genome characterization techniques, but a lack of knowledge of the hybridization properties of short duplexes hinders...
7.
Tang K, Taranenko N, Allman S, Chen C, Chang L, Jacobson K
Rapid Commun Mass Spectrom . 1994 Sep; 8(9):673-7. PMID: 7949332
We found that picolinic acid is a very good matrix for matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry of oligonucleotides, proteins and tRNA. Among the oligonucleotides, picolinic acid was shown...
8.
Sloop F, Brown G, Foote R, Jacobson K, Sachleben R
Bioconjug Chem . 1993 Sep; 4(5):406-9. PMID: 8274526
The synthesis of 3-(triethylstannyl)propanoic acid (TESPA), an organometallic reporter group that enables the mass labeling of oligonucleotides with stable isotopes of tin, is described. Synthesized from commercially available isotopically-enriched SnO2...
9.
Doktycz M, GIBSON W, Arlinghaus H, Allen R, Jacobson K
Appl Theor Electrophor . 1993 Jan; 3(3-4):157-62. PMID: 8512946
Development of alternative electrophoresis procedures are necessary for large volume sequencing and mapping studies. The use of stable isotopes as DNA labels and ultrathin gels promises to greatly increase the...
10.
Thundat T, Allison D, Warmack R, Brown G, Jacobson K, Schrick J, et al.
Scanning Microsc . 1992 Dec; 6(4):911-8. PMID: 1295085
Atomic force microscopy (AFM) was used to image circular DNA adsorbed on freshly cleaved mica and mica chemically modified with Mg(II), Co(II), La(III), and Zr(IV). Images obtained on unmodified mica...