K Allegaert
Overview
Explore the profile of K Allegaert including associated specialties, affiliations and a list of published articles.
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88
Citations
914
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Recent Articles
1.
Degraeuwe E, Persijn L, Nuytinck L, Allegaert K, De Taeye L, Gasthuys E, et al.
Acta Clin Belg
. 2023 Dec;
79(1):34-45.
PMID: 38054741
Paediatric clinical trials are critical to ensure that medications prescribed to children are safe and effective. However, evidence-based dosing and labelling of such medications remain limited, and most clinical trials...
2.
van der Heijden L, Mian P, Hias J, de Winter B, Tournoy J, Van der Linden L, et al.
Drugs Aging
. 2021 Dec;
39(1):83-95.
PMID: 34918212
Introduction: Paracetamol pharmacokinetics (PK) is highly variable in older fit adults after intravenous administration. Frailty and oral administration likely result in additional variability. The aim was to determine oral paracetamol...
3.
van Groen B, Nicolai J, Kuik A, Van Cruchten S, van Peer E, Smits A, et al.
Pharmacol Rev
. 2021 Feb;
73(2):597-678.
PMID: 33608409
The liver represents a major eliminating and detoxifying organ, determining exposure to endogenous compounds, drugs, and other xenobiotics. Drug transporters (DTs) and drug-metabolizing enzymes (DMEs) are key determinants of disposition,...
4.
Ceulemans M, Cuppers B, de Vries L, Allegaert K, Duvekot J, van Puijenbroek E
Ned Tijdschr Geneeskd
. 2021 Feb;
164.
PMID: 33560604
SARS-CoV-2 has rapidly spread worldwide since December 2019. Obviously, pregnant and lactating women will also be infected with SARS-CoV-2. Pregnant women, however, are a risk population for developing severe respiratory...
5.
Keij F, Kornelisse R, Tramper-Stranders G, Allegaert K
Future Microbiol
. 2020 May;
15:461-464.
PMID: 32378967
No abstract available.
6.
Caicedo A, De Wel O, Vandecappelle M, Thewissen L, Smits A, Allegaert K, et al.
Annu Int Conf IEEE Eng Med Biol Soc
. 2020 Jan;
2019:660-663.
PMID: 31945984
In this paper we explore the use of updated tensor decompositions for the monitoring of brain hemodynamics in neonates. For this study, we used concomitant measurements of heart rate, mean...
7.
Cristea S, Allegaert K, Falcao A, Falcao F, Silva R, Smits A, et al.
Antimicrob Agents Chemother
. 2019 Jun;
63(8).
PMID: 31182538
Ibuprofen and indomethacin are commonly used to induce ductus arteriosus closure in preterm neonates. Our group previously reported that ibuprofen decreased vancomycin clearance by 16%. In this study, we quantified...
8.
Russo F, Hooper S, Tibboel D, Dekoninck P, Benachi A, Treluyer J, et al.
Ultrasound Obstet Gynecol
. 2019 Feb;
53(2):274-275.
PMID: 30741452
No abstract available.
9.
Mian P, Valkenburg A, Allegaert K, Koch B, Breatnach C, Knibbe C, et al.
J Clin Pharmacol
. 2019 Jan;
59(6):847-855.
PMID: 30633373
Children undergoing cardiac surgery often receive acetaminophen (paracetamol) as part of their postoperative pain treatment. To date, there is no information on the pharmacokinetics (PK) of acetaminophen in this special...
10.
Mian P, van Esdonk M, Olkkola K, de Winter B, Liukas A, Spriet I, et al.
Br J Clin Pharmacol
. 2018 Oct;
85(1):126-135.
PMID: 30321459
Aims: Paracetamol is the analgesic most used by older people. The physiological changes occurring with ageing influence the pharmacokinetics (PK) of paracetamol and its variability. We performed a population PK-analysis...