K Aktories
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Explore the profile of K Aktories including associated specialties, affiliations and a list of published articles.
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237
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6056
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Recent Articles
1.
Zahaf N, Lang A, Kaiser L, Fichter C, Lassmann S, McCluskey A, et al.
Sci Rep
. 2017 Jan;
7:41252.
PMID: 28128281
The actin cytoskeleton is an attractive target for bacterial toxins. The ADP-ribosyltransferase TccC3 from the insect bacterial pathogen Photorhabdus luminescence modifies actin to force its aggregation. We intended to transport...
2.
Tabibzadeh S, Kong Q, Kapur S, Leffers H, Ridley A, Aktories K, et al.
Endocrine
. 2010 Dec;
3(8):549-56.
PMID: 21153131
TNF-α induced, in a time and dose-dependent fashion, cell-cell dissociation (dyscohesion) of endometrial epithelial cells. Within the time frame that dyscohesion was induced, TNF-α, in a dose-dependent fashion, reduced filamentous...
3.
Aktories K, Just I
Curr Top Microbiol Immunol
. 2005 Jun;
291:113-45.
PMID: 15981462
Rho proteins are master regulators of a large array of cellular functions, including control of cell morphology, cell migration and polarity, transcriptional activation, and cell cycle progression. They are the...
4.
Aktories K, Wilde C, Vogelsgesang M
Rev Physiol Biochem Pharmacol
. 2004 Sep;
152:1-22.
PMID: 15372308
C3-like exoenzymes comprise a family of seven bacterial ADP-ribosyltransferases, which selectively modify RhoA, B, and C at asparagine-41. Crystal structures of C3 exoenzymes are available, allowing novel insights into the...
5.
Waschke J, Baumgartner W, Adamson R, Zeng M, Aktories K, Barth H, et al.
Am J Physiol Heart Circ Physiol
. 2003 Sep;
286(1):H394-401.
PMID: 14512275
Our previous experiments indicated that GTPases, other than RhoA, are important for the maintenance of endothelial barrier integrity in both intact microvessels of rats and mice and cultured mouse myocardial...
6.
Adamson R, Curry F, Adamson G, Liu B, Jiang Y, Aktories K, et al.
J Physiol
. 2002 Feb;
539(Pt 1):295-308.
PMID: 11850521
Previous experiments using cultured endothelial monolayers indicate that Rho-family small GTPases are involved in modulation of endothelial monolayer permeability by regulating assembly of the cellular actin filament scaffold, activity of...
7.
Ballweber E, Galla M, Aktories K, Yeoh S, Weeds A, Mannherz H
FEBS Lett
. 2001 Nov;
508(1):131-5.
PMID: 11707283
Actin ADP-ribosylated at Arg177 was previously shown not to polymerise after increasing the ionic strength, but to cap the barbed ends of filaments. Here we confirm that the polymerisation of...
8.
Schmidt G, Goehring U, Schirmer J, Wilm M, Lohmann M, Giese A, et al.
Infect Immun
. 2001 Nov;
69(12):7663-70.
PMID: 11705946
Bordetella dermonecrotic toxin (DNT) catalyzes the transglutamination of glutamine-63/61 of Rho GTPases, thereby constitutively activating Rho proteins. Here we identified second substrates for transglutamination of RhoA by DNT. The enzymatically...
9.
Sorg I, Goehring U, Aktories K, Schmidt G
Infect Immun
. 2001 Nov;
69(12):7535-43.
PMID: 11705930
Yersinia enterocolitica, Yersinia pseudotuberculosis, and Yersinia pestis deliver different Yop (Yersinia outer proteins) effector proteins into mammalian cells by a type III secretion mechanism. Recently, it was shown that Yersinia...
10.
Tamma G, Klussmann E, Maric K, Aktories K, Svelto M, Rosenthal W, et al.
Am J Physiol Renal Physiol
. 2001 Nov;
281(6):F1092-101.
PMID: 11704560
First published August 8, 2001; 10.1152/ajprenal.00091.2001.-We have recently demonstrated that actin depolymerization is a prerequisite for cAMP-dependent translocation of the water channel aquaporin-2 (AQP2) into the apical membrane in AQP2-transfected...