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Jyoti Tanwar

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Articles 20
Citations 393
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Recent Articles
1.
Tanwar J, Ahuja K, Sharma A, Sehgal P, Ranjan G, Sultan F, et al.
PLoS Biol . 2024 Nov; 22(11):e3002895. PMID: 39527653
Mitochondria regulate several physiological functions through mitochondrial Ca2+ dynamics. However, role of mitochondrial Ca2+ signaling in melanosome biology remains unknown. Here, we show that pigmentation requires mitochondrial Ca2+ uptake. In...
2.
Tanwar J, Ahuja K, Sharma A, Sehgal P, Ranjan G, Sultan F, et al.
bioRxiv . 2023 Jun; PMID: 37292659
Mitochondria are versatile organelles that regulate several physiological functions. Many mitochondria-controlled processes are driven by mitochondrial Ca signaling. However, role of mitochondrial Ca signaling in melanosome biology remains unknown. Here,...
3.
Tanwar J, Sharma A, Saurav S, Shyamveer , Jatana N, Motiani R
J Biol Chem . 2022 Nov; 298(12):102681. PMID: 36356899
Stromal Interaction Molecule1 (STIM1) is an endoplasmic reticulum membrane-localized calcium (Ca) sensor that plays a critical role in the store-operated Ca entry (SOCE) pathway. STIM1 regulates a variety of physiological...
4.
Sultan F, Basu R, Murthy D, Kochar M, Attri K, Aggarwal A, et al.
PLoS Biol . 2022 May; 20(5):e3001634. PMID: 35584084
Therapeutic methods to modulate skin pigmentation has important implications for skin cancer prevention and for treating cutaneous hyperpigmentary conditions. Towards defining new potential targets, we followed temporal dynamics of melanogenesis...
5.
Tanwar J, Saurav S, Basu R, Singh J, Priya A, Dutta M, et al.
Cells . 2022 Feb; 11(4). PMID: 35203350
Inter-organellar communication is emerging as one of the most crucial regulators of cellular physiology. One of the key regulators of inter-organellar communication is Mitofusin-2 (MFN2). MFN2 is also involved in...
6.
Arora S, Tanwar J, Sharma N, Saurav S, Motiani R
Cancers (Basel) . 2021 Dec; 13(23). PMID: 34885048
Store operated Ca entry (SOCE) mediated by Orai1/2/3 channels is a highly regulated and ubiquitous Ca influx pathway. Although the role of Orai1 channels is well studied, the significance of...
7.
Saurav S, Tanwar J, Ahuja K, Motiani R
Mol Aspects Med . 2021 Jul; 81:101004. PMID: 34304899
Viral infections are one of the leading causes of human illness. Viruses take over host cell signaling cascades for their replication and infection. Calcium (Ca) is a versatile and ubiquitous...
8.
Sehgal P, Mathew S, Sivadas A, Ray A, Tanwar J, Vishwakarma S, et al.
EMBO J . 2021 Jun; 40(15):e107134. PMID: 34180064
Long non-coding RNAs (lncRNAs) are emerging as key regulators of endothelial cell function. Here, we investigated the role of a novel vascular endothelial-associated lncRNA (VEAL2) in regulating endothelial permeability. Precise...
9.
Tanwar J, Singh J, Motiani R
Mitochondrion . 2020 Dec; 57:9-22. PMID: 33316420
Mitochondria play vital role in regulating the cellular energetics and metabolism. Further, it is a signaling hub for cell survival and apoptotic pathways. One of the key determinants that calibrate...
10.
Tanwar J, Arora S, Motiani R
Cell Calcium . 2020 Jul; 90:102247. PMID: 32659517
Ion channels in particular Calcium (Ca) channels play a critical role in physiology by regulating plethora of cellular processes ranging from cell proliferation, differentiation, transcriptional regulation and programmed cell death....