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Jyllian N Kemsley

Explore the profile of Jyllian N Kemsley including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Decker A, Chow M, Kemsley J, Lehnert N, Solomon E
J Am Chem Soc . 2006 Apr; 128(14):4719-33. PMID: 16594709
Bleomycin (BLM), a glycopeptide antibiotic chemotherapy agent, is capable of single- and double-strand DNA damage. Activated bleomycin (ABLM), a low-spin Fe(III)-OOH complex, is the last intermediate detected prior to DNA...
2.
Kemsley J, Zaleski K, Chow M, Decker A, Shishova E, Wasinger E, et al.
J Am Chem Soc . 2003 Sep; 125(36):10810-21. PMID: 12952460
Bleomycin is an antibiotic used in cancer chemotherapy for its ability to achieve both single- and double-strand cleavage of DNA through abstraction of the deoxyribose C4'-H. Magnetic circular dichroism (MCD)...
3.
Kemsley J, Wasinger E, Datta S, Mitic N, Acharya T, Hedman B, et al.
J Am Chem Soc . 2003 May; 125(19):5677-86. PMID: 12733906
Phenylalanine hydroxylase (PAH) is a tetrahydrobiopterin-dependent, nonheme iron enzyme that catalyzes the hydroxylation of L-Phe to L-Tyr in the rate-limiting step of phenylalanine catabolism. This reaction is tightly coupled in...