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Justine Pasanisi

Explore the profile of Justine Pasanisi including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 49
Followers 0
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Recent Articles
1.
Bello R, Pacchiardi K, Chauvel C, Ades L, Braun T, Pasanisi J, et al.
Hemasphere . 2022 Dec; 7(1):e819. PMID: 36570694
No abstract available.
2.
Duchmann M, Joudinaud R, Boudry A, Pasanisi J, Di Feo G, Kim R, et al.
Blood Cancer J . 2022 Sep; 12(9):136. PMID: 36151081
No abstract available.
3.
Bello R, Pasanisi J, Joudinaud R, Duchmann M, Pardieu B, Ayaka P, et al.
Blood Cancer J . 2022 Jun; 12(6):95. PMID: 35750691
Functional precision medicine in AML often relies on short-term in vitro drug sensitivity screening (DSS) of primary patient cells in standard culture conditions. We designed a niche-like DSS assay combining...
4.
Pardieu B, Pasanisi J, Ling F, Bello R, Penneroux J, Su A, et al.
Leukemia . 2022 Apr; 36(6):1585-1595. PMID: 35474100
By querying metabolic pathways associated with leukemic stemness and survival in multiple AML datasets, we nominated SLC7A11 encoding the xCT cystine importer as a putative AML dependency. Genetic and chemical...
5.
Su A, Ling F, Vaganay C, Sodaro G, Benaksas C, Bello R, et al.
Cancer Discov . 2020 Aug; 10(12):1894-1911. PMID: 32826232
Deciphering the impact of metabolic intervention on response to anticancer therapy may elucidate a path toward improved clinical responses. Here, we identify amino acid-related pathways connected to the folate cycle...
6.
Cerrano M, Duchmann M, Kim R, Vasseur L, Hirsch P, Thomas X, et al.
Leukemia . 2020 Jun; 35(3):712-723. PMID: 32581253
Intra-tumor heterogeneity portends poor outcome in many cancers. In AML, a higher number of drivers worsens prognosis. The Shannon Index is a robust metric of clonal heterogeneity that accounts for...
7.
Masse A, Roulin L, Pasanisi J, Penneroux J, Gachet S, Delord M, et al.
Leuk Res . 2019 Nov; 87:106269. PMID: 31751766
Bromodomain and Extra-Terminal inhibitors (BETi) such as OTX015 are active in Acute Myeloid Leukaemias (AML). Their activity on Leukemic Stem Cells (LSCs) is less documented. We interrogated the anti-LSC activity...