Justin K Murray
Overview
Explore the profile of Justin K Murray including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
23
Citations
391
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Guo Y, Gao Z, LaGory E, Kristin L, Gupte J, Gong Y, et al.
Hepatol Commun
. 2024 May;
8(5).
PMID: 38696369
Background: Human genetic studies have identified several mitochondrial amidoxime-reducing component 1 (MTARC1) variants as protective against metabolic dysfunction-associated steatotic liver disease. The MTARC1 variants are associated with decreased plasma lipids...
2.
Kazarian A, Barnhart W, Long J, Sham K, Wu B, Murray J
J Chromatogr A
. 2021 Dec;
1661:462679.
PMID: 34871941
N-acetylgalactosamine (GalNAc)-modified small interfering ribonucleic acids (siRNA) have shown promising outcomes for targeted siRNA delivery resulting in gene silencing in vivo; however, their structural complexity requires development of new purification...
3.
Murray J, Long J, Liu L, Singh S, Pruitt D, Ollmann M, et al.
Nucleic Acid Ther
. 2021 Jul;
31(5):324-340.
PMID: 34297902
Human genome wide association studies confirm the association of the rs738409 single nucleotide polymorphism (SNP) in the gene encoding protein patatin like phospholipase domain containing 3 () with nonalcoholic fatty...
4.
Kazarian A, Barnhart W, Campuzano I, Cabrera J, Fitch T, Long J, et al.
J Chromatogr A
. 2020 Nov;
1634:461633.
PMID: 33189959
The current study investigates a method for purification of the G-quadruplex secondary structure, naturally formed by a guanine-rich 21-mer oligonucleotide strand using a monolithic convective interaction media-quaternary amine (CIM-QA) column...
5.
Murray J, Wu B, Tegley C, Nixey T, Falsey J, Herberich B, et al.
ACS Chem Biol
. 2019 Mar;
14(4):806-818.
PMID: 30875193
Drug discovery research on new pain targets with human genetic validation, including the voltage-gated sodium channel Na1.7, is being pursued to address the unmet medical need with respect to chronic...
6.
Wu B, Murray J, Andrews K, Sham K, Long J, Aral J, et al.
J Med Chem
. 2018 Oct;
61(21):9500-9512.
PMID: 30346167
Inhibitors of the voltage-gated sodium channel Na1.7 are being investigated as pain therapeutics due to compelling human genetics. We previously identified Na1.7-inhibitory peptides GpTx-1 and JzTx-V from tarantula venom screens....
7.
Moyer B, Murray J, Ligutti J, Andrews K, Favreau P, Jordan J, et al.
PLoS One
. 2018 May;
13(5):e0196791.
PMID: 29723257
Identification of voltage-gated sodium channel NaV1.7 inhibitors for chronic pain therapeutic development is an area of vigorous pursuit. In an effort to identify more potent leads compared to our previously...
8.
Biswas K, Nixey T, Murray J, Falsey J, Yin L, Liu H, et al.
ACS Chem Biol
. 2017 Aug;
12(9):2427-2435.
PMID: 28800217
The voltage-gated sodium channel Na1.7 is a genetically validated pain target under investigation for the development of analgesics. A therapeutic with a less frequent dosing regimen would be of value...
9.
Murray J, Long J, Zou A, Ligutti J, Andrews K, Poppe L, et al.
J Med Chem
. 2016 Feb;
59(6):2704-17.
PMID: 26890998
There is interest in the identification and optimization of new molecular entities selectively targeting ion channels of therapeutic relevance. Peptide toxins represent a rich source of pharmacology for ion channels,...
10.
Murray J, Qian Y, Liu B, Elliott R, Aral J, Park C, et al.
J Med Chem
. 2015 Aug;
58(17):6784-802.
PMID: 26288216
To realize the medicinal potential of peptide toxins, naturally occurring disulfide-rich peptides, as ion channel antagonists, more efficient pharmaceutical optimization technologies must be developed. Here, we show that the therapeutic...