Jurgen Grassler
Overview
Explore the profile of Jurgen Grassler including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
7926
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Recent Articles
1.
Jarzebska N, Rodionov R, Voit-Bak K, Straube R, Mucke A, Tselmin S, et al.
Horm Metab Res
. 2025 Jan;
PMID: 39788160
Neutrophil extracellular traps (NETs) are large structures composed of chromatin, histones and granule-derived proteins released extracellularly by neutrophils. They are generally considered to be a part of the antimicrobial defense...
2.
Tam J, Hoffmann T, Fischer S, Bornstein S, Grassler J, Noack B
PLoS One
. 2018 Oct;
13(10):e0204724.
PMID: 30273364
Background And Objective: The involvement of the oral microbiota as a possible link between periodontitis, type 2 diabetes mellitus and obesity is still not well understood. The objective of the...
3.
Ried J, Jeff M J, Chu A, Bragg-Gresham J, Dongen J, Huffman J, et al.
Nat Commun
. 2016 Nov;
7:13357.
PMID: 27876822
Large consortia have revealed hundreds of genetic loci associated with anthropometric traits, one trait at a time. We examined whether genetic variants affect body shape as a composite phenotype that...
4.
Ehret G, Ferreira T, Chasman D, Jackson A, Schmidt E, Johnson T, et al.
Nat Genet
. 2016 Sep;
48(10):1171-1184.
PMID: 27618452
To dissect the genetic architecture of blood pressure and assess effects on target organ damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 individuals of European ancestry,...
5.
Winkler T, Justice A, Graff M, Barata L, Feitosa M, Chu S, et al.
PLoS Genet
. 2016 Jun;
12(6):e1006166.
PMID: 27355579
[This corrects the article DOI: 10.1371/journal.pgen.1005378.].
6.
Winkler T, Justice A, Graff M, Barata L, Feitosa M, Chu S, et al.
PLoS Genet
. 2015 Oct;
11(10):e1005378.
PMID: 26426971
Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body...
7.
Locke A, Kahali B, Berndt S, Justice A, Pers T, Day F, et al.
Nature
. 2015 Feb;
518(7538):197-206.
PMID: 25673413
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index...
8.
Shungin D, Winkler T, Croteau-Chonka D, Ferreira T, Locke A, Magi R, et al.
Nature
. 2015 Feb;
518(7538):187-196.
PMID: 25673412
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat...
9.
Wood A, Esko T, Yang J, Vedantam S, Pers T, Gustafsson S, et al.
Nat Genet
. 2014 Oct;
46(11):1173-86.
PMID: 25282103
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in...
10.
Scott R, Chu A, Grarup N, Manning A, Hivert M, Shungin D, et al.
Diabetes
. 2012 Mar;
61(5):1291-6.
PMID: 22415877
Gene-lifestyle interactions have been suggested to contribute to the development of type 2 diabetes. Glucose levels 2 h after a standard 75-g glucose challenge are used to diagnose diabetes and...