Jurgen A H R Claassen
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Explore the profile of Jurgen A H R Claassen including associated specialties, affiliations and a list of published articles.
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158
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4058
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Recent Articles
1.
Palsma T, Claassen J, Richard E, de Heus R
J Hypertens
. 2025 Feb;
PMID: 40008517
Background: Higher blood pressure variability (BPV) is associated with adverse clinical outcomes but lack of standardized methodology hampers clinical translation. Day-to-day BPV seems most promising for an older population, especially...
2.
Alders P, Kok A, van Zutphen E, Claassen J, Deeg D
J Prev Alzheimers Dis
. 2025 Jan;
12(2):100024.
PMID: 39863328
Background: Few studies have addressed the association of sleep disturbances with incident dementia with long lag times. We add to this literature by investigating how lag times varying from 2.2...
3.
Wiersinga J, Jansen S, Peters M, Rhodius-Meester H, Trappenburg M, Claassen J, et al.
Lancet Reg Health Eur
. 2024 Dec;
48:101154.
PMID: 39717228
Hypertension and orthostatic hypotension (OH) frequently coexist in the older population, both stemming from impaired blood pressure (BP) regulation. Managing hypertension in patients with OH presents a significant clinical challenge,...
4.
van Hattem T, Verkaar L, Krugliakova E, Adelhofer N, Zeising M, Drinkenburg W, et al.
Physiology (Bethesda)
. 2024 Nov;
40(3).
PMID: 39601891
Sleep has been postulated to play an important role in the removal of potentially neurotoxic molecules, such as amyloid-β, from the brain via the glymphatic system. Disturbed sleep, on the...
5.
Mentink L, van Osch M, Bakker L, Olde Rikkert M, Beckmann C, Claassen J, et al.
Geroscience
. 2024 Nov;
PMID: 39531187
The mechanism underlying the possible causal association between long-term sleep disruption and Alzheimer's disease remains unclear Musiek et al. 2015. A hypothesised pathway through increased brain amyloid load was not...
6.
Sole-Guardia G, Luijten M, Janssen E, Visch R, Geenen B, Kusters B, et al.
Brain Pathol
. 2024 Aug;
35(2):e13301.
PMID: 39175459
The major vascular cause of dementia is cerebral small vessel disease (SVD). Its diagnosis relies on imaging hallmarks, such as white matter hyperintensities (WMH). WMH present a heterogenous pathology, including...
7.
Al-Shama R, Uleman J, Pereira M, Claassen J, Dresler M
Sleep Med Rev
. 2024 Aug;
77:101977.
PMID: 39096646
Sleep plays an essential role in physiology, allowing the brain and body to restore itself. Despite its critical role, our understanding of the underlying processes in the sleeping human brain...
8.
van Setten A, Uleman J, Melis R, Lawlor B, Riksen N, Claassen J, et al.
Geroscience
. 2024 Jul;
47(1):1093-1104.
PMID: 39085534
Introduction: Systemic inflammation and endothelial dysfunction are potentially modifiable factors implicated in Alzheimer's disease (AD), which offer potential therapeutic targets to slow disease progression. Methods: We investigated the relationship between...
9.
Klop M, Claassen J, Floor-Westerdijk M, van Wezel R, Maier A, Meskers C
Geroscience
. 2024 Jun;
46(6):6331-6346.
PMID: 38890204
Orthostatic hypotension (OH) is prevalent in older adults and can cause falls and hospitalization. Diagnostic intermittent blood pressure (BP) measurements are only a proxy for cerebral perfusion and do not...
10.
Deckers K, Zwan M, Soons L, Waterink L, Beers S, van Houdt S, et al.
Alzheimers Res Ther
. 2024 Jun;
16(1):126.
PMID: 38872204
Background: Evidence on the effectiveness of multidomain lifestyle interventions to prevent cognitive decline in older people without dementia is mixed. Embedded in the World-Wide FINGERS initiative, FINGER-NL aims to investigate...