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Jurg A Sigrist

Explore the profile of Jurg A Sigrist including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 126
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Recent Articles
1.
Reynaert E, Nagappa D, Sigrist J, Morgenroth E
Water Res X . 2024 Jun; 22:100215. PMID: 38831972
A growing number of cities and regions are promoting or mandating on-site treatment and reuse of wastewater, which has resulted in the implementation of several thousand on-site water reuse systems...
2.
Besmer M, Hammes F, Sigrist J, Ort C
Front Microbiol . 2017 Dec; 8:2229. PMID: 29213255
Monitoring of microbial drinking water quality is a key component for ensuring safety and understanding risk, but conventional monitoring strategies are typically based on low sampling frequencies (e.g., quarterly or...
3.
Besmer M, Sigrist J, Props R, Buysschaert B, Mao G, Boon N, et al.
Front Microbiol . 2017 Nov; 8:1900. PMID: 29085343
Rapid contamination of drinking water in distribution and storage systems can occur due to pressure drop, backflow, cross-connections, accidents, and bio-terrorism. Small volumes of a concentrated contaminant (e.g., wastewater) can...
4.
Page R, Besmer M, Epting J, Sigrist J, Hammes F, Huggenberger P
Sci Total Environ . 2017 May; 599-600:227-236. PMID: 28477479
We have studied the dynamics of water quality in three karst springs taking advantage of new technological developments that enable high-resolution measurements of bacterial load (total cell concentration: TCC) as...
5.
Besmer M, Epting J, Page R, Sigrist J, Huggenberger P, Hammes F
Sci Rep . 2016 Dec; 6:38462. PMID: 27924920
Detailed measurements of physical, chemical and biological dynamics in groundwater are key to understanding the important processes in place and their influence on water quality - particularly when used for...
6.
Besmer M, Weissbrodt D, Kratochvil B, Sigrist J, Weyland M, Hammes F
Front Microbiol . 2014 Jun; 5:265. PMID: 24917858
Fluorescent staining coupled with flow cytometry (FCM) is often used for the monitoring, quantification and characterization of bacteria in engineered and environmental aquatic ecosystems including seawater, freshwater, drinking water, wastewater,...
7.
Rechsteiner M, Berger C, Zauner L, Sigrist J, Weber M, Longnecker R, et al.
J Virol . 2007 Dec; 82(4):1739-47. PMID: 18057232
The B-lymphotropic Epstein-Barr virus (EBV) encodes two isoforms of latent membrane protein 2 (LMP2), LMP2A and LMP2B, which are expressed during latency in B cells. The function of LMP2B is...
8.
Rechsteiner M, Berger C, Weber M, Sigrist J, Nadal D, Bernasconi M
J Gen Virol . 2007 Apr; 88(Pt 5):1454-1459. PMID: 17412973
Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A) blocks B-cell receptor (BCR) signalling after BCR cross-linking to inhibit activation of lytic EBV, and ectopically expressed LMP2B negatively regulates LMP2A. Here,...
9.
Rao S, Rechsteiner M, Berger C, Sigrist J, Nadal D, Bernasconi M
Mol Cancer . 2007 Jan; 6:3. PMID: 17214905
Epigenetic silencing of regulatory genes by aberrant methylation contributes to tumorigenesis. DNA methyltransferase inhibitors (DNMTI) represent promising new drugs for anti-cancer therapies. The DNMTI 5-Azacytidine is effective against myelodysplastic syndrome,...
10.
Bernasconi M, Berger C, Sigrist J, Bonanomi A, Sobek J, Niggli F, et al.
Virol J . 2006 Jun; 3:43. PMID: 16756670
Background: The Epstein-Barr virus (EBV) is associated with lymphoid malignancies, including Burkitt's lymphoma (BL), and can transform human B cells in vitro. EBV-harboring cell lines are widely used to investigate...