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Junxiao Deng

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Articles 8
Citations 149
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Recent Articles
1.
Li N, Ma M, Lai M, Gu L, Kang M, Wang Z, et al.
J Diabetes . 2021 Dec; 14(2):111-120. PMID: 34889059
Background: The aim of our research was to prospectively explore the clinical value of a deep learning algorithm (DLA) to detect referable diabetic retinopathy (DR) in different subgroups stratified by...
2.
Yang X, Zhu X, Ji H, Deng J, Lu P, Jiang Z, et al.
Mol Med Rep . 2017 Dec; 17(2):2501-2508. PMID: 29207194
Highly active antiretroviral therapy (HAART) is very effective in suppressing human immunodeficiency virus type 1 (HIV‑1) replication. However, the treatment is required to be administered for the remainder of an...
3.
Deng J, Qu X, Lu P, Yang X, Zhu Y, Ji H, et al.
Mol Ther Nucleic Acids . 2017 Mar; 6:233-242. PMID: 28325289
HIV-1 inserts its proviral DNA into the infected host cells, by which HIV proviral DNA can then be duplicated along with each cell division. Thus, provirus cannot be eradicated completely...
4.
Lu P, Qu X, Shen Y, Jiang Z, Wang P, Zeng H, et al.
Sci Rep . 2016 Apr; 6:24100. PMID: 27067814
None of the currently used anti-HIV-1 agents can effectively eliminate latent HIV-1 reservoirs, which is a major hurdle to a complete cure for AIDS. We report here that a novel...
5.
Ji H, Jiang Z, Lu P, Ma L, Li C, Pan H, et al.
Mol Ther . 2016 Jan; 24(3):508-21. PMID: 26775808
HIV-1 escapes antiretroviral agents by integrating into the host DNA and forming a latent transcriptionally silent HIV-1 provirus. Transcriptional activation is prerequisite for reactivation and the eradication of latent HIV-1...
6.
Wang P, Qu X, Zhou X, Shen Y, Ji H, Fu Z, et al.
Virology . 2015 Oct; 486:228-38. PMID: 26469550
Understanding the mechanism of HIV-1 latency is crucial to the viral reservoir eradication. Human cellular miRNAs can modulate HIV-1 expression by targeting of viral RNAs or host gene transcripts. To...
7.
Deng J, Chen Y, Ding D, Lu P, Yang X, Song Z, et al.
AIDS Res Hum Retroviruses . 2015 Sep; 31(12):1213-8. PMID: 26398573
TRIM5α is an antiviral factor that can greatly limit HIV-1 infection. Although several researchers have investigated whether TRIM5α H43Y polymorphism influences the risk of HIV-1 infection, no definite conclusion has...
8.
Wang X, Wang P, Fu Z, Ji H, Qu X, Zeng H, et al.
AIDS Res Hum Retroviruses . 2014 Nov; 31(1):98-106. PMID: 25403229
HIV latency is the foremost barrier to clearing HIV infection from patients. Reactivation of latent HIV-1 represents a promising strategy to deplete these viral reservoirs. Here, we report a novel...