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Junkang Jiang

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Articles 27
Citations 271
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Recent Articles
1.
Yu S, Li Z, Zhang Q, Wang R, Zhao Z, Ding W, et al.
Ecotoxicol Environ Saf . 2022 Mar; 234:113413. PMID: 35305351
Exposure to antimony (Sb), recently identified as a nerve pollutant, can result in neuron damage; but, associated-neurotoxicological mechanisms were still not clear. Herein, we assessed the role of ferroptosis in...
2.
Qu J, Han Y, Zhao Z, Wu Y, Lu Y, Chen G, et al.
Toxicology . 2021 Jul; 460:152871. PMID: 34303733
Perfluorooctane sulfonate (PFOS) is a widespread persistent organic pollutant. Both epidemiological survey and our previous in vivo study have revealed the associations between PFOS exposure and spermatogenesis disorder, while the...
3.
Xu S, Yang Z, Zhi Y, Yu S, Zhang T, Jiang J, et al.
Sci Total Environ . 2020 Nov; 760:143235. PMID: 33183805
We have previously identified antimony (Sb) as a newly nerve poison which leads to neuronal apoptosis. However, the relationship between Sb exposure and Alzheimer's disease (AD) process lacks direct evidence....
4.
Zhi Y, Lu C, Zhu G, Li Z, Zhu P, Liu Y, et al.
Neurotoxicology . 2020 Sep; 81:101-108. PMID: 32920012
Antimony (Sb) is a potentially toxic chemical element abundantly found in the environment. We previously reported that Sb promoted neuronal deathvia reactive oxygen species-dependent autophagy. Here, we assessed the role...
5.
Shi W, Tang Y, Zhi Y, Li Z, Yu S, Jiang J, et al.
Sci Total Environ . 2020 Aug; 737:140252. PMID: 32783850
Antimony (Sb), as a newly identified nerve poison, can lead to neuronal apoptosis. However, its neurotoxicological mechanisms remain largely unclear. Here, we evaluated the role and regulation of Wnt/β-catenin pathway...
6.
Wu Y, Jin Y, Sun T, Zhu P, Li J, Zhang Q, et al.
J Nanobiotechnology . 2020 May; 18(1):77. PMID: 32429946
Background: Most nanoparticles (NPs) reportedly block autophagic flux, thereby upregulating p62/SQSTM1 through degradation inhibition. p62 also acts as a multifunctional scaffold protein with multiple domains, and is involved in various...
7.
Zhu G, Liu Y, Zhi Y, Jin Y, Li J, Shi W, et al.
Toxicol Lett . 2019 Apr; 309:10-19. PMID: 30951808
Although manganese (Mn) is an essential trace element, its excessive consumption may lead to neuronal death and neurodegenerative disorders. Human cells launch adaptive responses to attenuate Mn-induced neurotoxicity. However, the...
8.
Zhao X, Liu Y, Zhu G, Liang Y, Liu B, Wu Y, et al.
Sci Total Environ . 2018 Sep; 646:1047-1055. PMID: 30235590
Manganese (Mn) is an essential trace element. Excessive exposure to Mn may lead to neuronal death and neurodegenerative disorders. Accumulating evidence has shown that silent mating type information regulation 2 ...
9.
Yin L, Dai Q, Jiang P, Zhu L, Dai H, Yao Z, et al.
Neurotoxicology . 2017 Apr; 64:195-203. PMID: 28385490
Chronic manganese (Mn) exposure can lead to neuroinflammation and neurological deficit, which resemble idiopathic Parkinson's disease (IPD). However, the precise mechanisms underlying Mn exposure-induced neurotoxicity remain incompletely understood. Microglia can...
10.
Liu X, Yang J, Lu C, Jiang S, Nie X, Han J, et al.
Neurochem Int . 2017 Feb; 108:40-51. PMID: 28232070
Manganese (Mn) is a widely distributed trace element that is essential for normal brain function and development. However, chronic exposure to excessive Mn has been known to lead to neuronal...