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Junichi Yuasa-Kawada

Explore the profile of Junichi Yuasa-Kawada including associated specialties, affiliations and a list of published articles. Areas
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Citations 262
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Recent Articles
1.
Yuasa-Kawada J, Kinoshita-Kawada M, Hiramoto M, Yamagishi S, Mishima T, Yasunaga S, et al.
Neural Regen Res . 2025 Feb; PMID: 39995079
The nervous system processes a vast amount of information, performing computations that underlie perception, cognition, and behavior. During development, neuronal guidance genes, which encode extracellular cues, their receptors, and downstream...
2.
Mishima T, Yuasa-Kawada J, Fujioka S, Tsuboi Y
Biomedicines . 2024 Jan; 12(1). PMID: 38255218
With technological applications, especially in genetic testing, new diseases have been discovered and new disease concepts have been proposed in recent years; however, the pathogenesis and treatment of these rare...
3.
Yuasa-Kawada J, Kinoshita-Kawada M, Tsuboi Y, Wu J
Protein Cell . 2023 Mar; 14(4):238-261. PMID: 36942388
Neurons migrate from their birthplaces to the destinations, and extending axons navigate to their synaptic targets by sensing various extracellular cues in spatiotemporally controlled manners. These evolutionally conserved guidance cues...
4.
Deshimaru M, Mishima T, Watanabe T, Kubota K, Hosoi M, Kinoshita-Kawada M, et al.
Neurosci Lett . 2021 Sep; 764:136234. PMID: 34508845
Perry disease (Perry syndrome) is a rare, rapidly progressive, autosomal dominant neurodegenerative disease characterized by parkinsonism, depression/apathy, weight loss, and respiratory symptoms including central hypoventilation. It is caused by missense...
5.
Deshimaru M, Kinoshita-Kawada M, Kubota K, Watanabe T, Tanaka Y, Hirano S, et al.
Int J Mol Sci . 2021 Apr; 22(8). PMID: 33924373
A common pathological hallmark of several neurodegenerative diseases, including amyotrophic lateral sclerosis, is cytoplasmic mislocalization and aggregation of nuclear RNA-binding protein TDP-43. Perry disease, which displays inherited atypical parkinsonism, is...
6.
Kinoshita-Kawada M, Hasegawa H, Hongu T, Yanagi S, Kanaho Y, Masai I, et al.
Bio Protoc . 2021 Mar; 9(18):e3373. PMID: 33654869
Developing axons change responsiveness to guidance cues during the journey to synapse with target cells. Axon crossing at the ventral midline serves as a model for studying how axons accomplish...
7.
Kinoshita-Kawada M, Hasegawa H, Hongu T, Yanagi S, Kanaho Y, Masai I, et al.
Development . 2019 Jan; 146(3). PMID: 30674481
A switch in the response of commissural axons to the repellent Slit is crucial for ensuring that they cross the ventral midline only once. However, the underlying mechanisms remain to...
8.
Mishima T, Fujioka S, Fukae J, Yuasa-Kawada J, Tsuboi Y
Int J Mol Sci . 2018 Dec; 19(12). PMID: 30518093
Parkinson's disease (PD) and atypical parkinsonian syndromes are age-dependent multifactorial neurodegenerative diseases, which are clinically characterized by bradykinesia, tremor, muscle rigidity and postural instability. Although these diseases share several common...
9.
Mishima T, Deshimaru M, Watanabe T, Kubota K, Kinoshita-Kawada M, Yuasa-Kawada J, et al.
Neurosci Lett . 2017 Dec; 666:98-103. PMID: 29273399
Perry syndrome is a rare neurodegenerative disease characterized by parkinsonism, depression/apathy, weight loss, and central hypoventilation. Our previously-conducted genome-wide association scan and subsequent studies identified nine mutations in DCTN1, the...
10.
Nishiwaki Y, Yoshizawa A, Kojima Y, Oguri E, Nakamura S, Suzuki S, et al.
Dev Cell . 2013 Jun; 25(4):374-87. PMID: 23725763
Intracellular vesicular transport is important for photoreceptor function and maintenance. However, the mechanism underlying photoreceptor degeneration in response to vesicular transport defects is unknown. Here, we report that photoreceptors undergo...