Junghuei Chen
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    Explore the profile of Junghuei Chen including associated specialties, affiliations and a list of published articles.
           
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              Citations
              50
            
            
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  Recent Articles
          1.
        
    
    Padilla J, Sha R, Kristiansen M, Chen J, Jonoska N, Seeman N
  
  
    Angew Chem Int Ed Engl
    . 2015 Mar;
          54(20):5939-42.
    
    PMID: 25810302
  
  
          DNA nanostructured tiles play an active role in their own self-assembly in the system described herein whereby they initiate a binding event that produces a cascading assembly process. We present...
      
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    Lee J, Chen J, Deaton R, Kim J
  
  
    J Biol Eng
    . 2014 Nov;
          8(1):25.
    
    PMID: 25414728
  
  
          Background: Genetic material extracted from in situ microbial communities has high promise as an indicator of biological system status. However, the challenge is to access genomic information from all organisms...
      
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    Liu Y, Chen J, Teplyakov A
  
  
    Langmuir
    . 2012 Oct;
          28(44):15521-8.
    
    PMID: 23025426
  
  
          In developing novel designs for semiconductor-based biosensors and for biofunctionalization of semiconductors in general, it is extremely important to be able to block the reaction sites present on a surface...
      
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    Tsai Y, Wang Y, Urena D, Kumar S, Chen J
  
  
    DNA Repair (Amst)
    . 2011 Jan;
          10(4):363-72.
    
    PMID: 21239234
  
  
          Human Rad51 (hRad51) promoted homology recognition and subsequent strand exchange are the key steps in human homologous recombination mediated repair of DNA double-strand breaks. However, it is still not clear...
      
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    Urena D, Zhang Z, Tsai Y, Wang Y, Chen J
  
  
    J Mol Biol
    . 2010 Nov;
          405(1):77-91.
    
    PMID: 21056573
  
  
          Rad51 and Rad54 play crucial roles during homologous recombination. The biochemical activities of human Rad51 (hRad51) and human Rad54 (hRad54) and their interactions with each other are well documented. However,...
      
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    Wang Y, Tsai Y, Urena-Rivera E, Chen J
  
  
    Protein Expr Purif
    . 2007 Dec;
          58(1):122-31.
    
    PMID: 18068376
  
  
          Topoisomerase II of kinetoplastid parasites plays an important role in the replication of unusual networks of kinetoplast DNA (kDNA) and is a very useful target for antiparasitic drugs. In this...
      
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    Tsai Y, Yu B, Wang Y, Chen J, Jain M
  
  
    Biochim Biophys Acta
    . 2006 May;
          1758(5):653-65.
    
    PMID: 16730646
  
  
          The changes in the microenvironment of the Trp-3 on the i-face of pig pancreatic IB phospholipase A2 (PLA2) provide a measure of the tight contact (Ramirez and Jain, Protein Sci....
      
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    Yoon D, Wang Y, Stapleford K, Wiesmuller L, Chen J
  
  
    J Mol Biol
    . 2004 Apr;
          336(3):639-54.
    
    PMID: 15095978
  
  
          We explore the effects of p53 on strand exchange as well as regression of stalled replication forks promoted by human Rad51. We have found that p53 specifically inhibits strand exchange...
      
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    Prabhu V, Simons A, Iwasaki H, Gai D, Simmons D, Chen J
  
  
    J Mol Biol
    . 2002 Mar;
          316(5):1023-32.
    
    PMID: 11884140
  
  
          The Holliday junction is the central intermediate in homologous recombination. Branch migration of this four-stranded DNA structure is a key step in genetic recombination that affects the extent of genetic...