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Jung-Min Pyun

Explore the profile of Jung-Min Pyun including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 222
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Recent Articles
1.
Han S, Hwang J, Park T, Pyun J, Lee J, Park J, et al.
Alzheimers Dement . 2025 Feb; 21(2):e14563. PMID: 39935412
Introduction: The molecular mechanisms underlying early-onset Alzheimer's disease (EOAD) and late-onset Alzheimer's disease (LOAD) remain incompletely understood, particularly in Asian populations. Methods: RNA-sequencing was carried out on blood samples from...
2.
Pyun J, Lee I, Lee K, Kim M, Park C, Yang H
Dement Neurocogn Disord . 2024 Nov; 23(4):202-211. PMID: 39512703
Background And Purpose: Choline alfoscerate (CA) is an acetylcholine precursor known for its beneficial effect on cognition in patient with Alzheimer's disease dementia (ADD). However, there is little evidence of...
3.
Pyun J, Park Y, Kang M, Kim S
Alzheimers Res Ther . 2024 Oct; 16(1):210. PMID: 39358798
Background: Cholinesterase inhibitors (ChEIs) are prescribed for Alzheimer's disease (AD) and sometimes for mild cognitive impairment (MCI) without knowing underlying pathologies and its effect on cognition. We investigated the frequency...
4.
Lee M, Lee E, Kim R, Pyun J, Joo B, Kwon K, et al.
Clin Neurol Neurosurg . 2024 Feb; 238:108182. PMID: 38417245
Objectives: Although the systemic immune-inflammatory index (SII) has recently been correlated with stroke severity and functional outcome, the underlying pathogenesis remains largely unknown. The objective of this study was to...
5.
Shim K, Kim D, Kang M, Pyun J, Park Y, Youn Y, et al.
Alzheimers Dement . 2024 Feb; 20(4):2731-2741. PMID: 38411315
Introduction: Alzheimer's disease (AD) involves the complement cascade, with complement component 3 (C3) playing a key role. However, the relationship between C3 and amyloid beta (Aβ) in blood is limited....
6.
Pyun J, Park Y, Youn Y, Kang M, Shim K, Jang J, et al.
Transl Psychiatry . 2024 Feb; 14(1):88. PMID: 38341444
Various plasma biomarkers for amyloid-β (Aβ) have shown high predictability of amyloid PET positivity. However, the characteristics of discordance between amyloid PET and plasma Aβ42/40 positivity are poorly understood. Thorough...
7.
Han S, Pyun J, Bice P, Bennett D, Saykin A, Kim S, et al.
Alzheimers Res Ther . 2024 Jan; 16(1):5. PMID: 38195609
Background: Alzheimer's dementia (AD) pathogenesis involves complex mechanisms, including microRNA (miRNA) dysregulation. Integrative network and machine learning analysis of miRNA can provide insights into AD pathology and prognostic/diagnostic biomarkers. Methods:...
8.
Han S, Pyun J, Bice P, Bennett D, Saykin A, Kim S, et al.
Res Sq . 2023 Nov; PMID: 37961387
Background: Alzheimer's dementia (AD) pathogenesis involves complex mechanisms, including microRNA (miRNA) dysregulation. Integrative network and machine learning analysis of miRNA can provide insights into AD pathology and prognostic/diagnostic biomarkers. Methods:...
9.
Ju H, Joo B, Pyun J, Kwon K
Geriatr Gerontol Int . 2023 Sep; 23(11):877-879. PMID: 37721040
No abstract available.
10.
Pyun J, Park Y, Wang J, Bennett D, Bice P, Kim J, et al.
Alzheimers Dement . 2023 Aug; 20(1):243-252. PMID: 37563770
Introduction: Our previously developed blood-based transcriptional risk scores (TRS) showed associations with diagnosis and neuroimaging biomarkers for Alzheimer's disease (AD). Here, we developed brain-based TRS. Methods: We integrated AD genome-wide...