Jung-Eun Jang
Overview
Explore the profile of Jung-Eun Jang including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
14
Citations
1415
Followers
0
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Recent Articles
1.
Daley D, Zambirinis C, Seifert L, Akkad N, Mohan N, Werba G, et al.
Cell
. 2020 Nov;
183(4):1134-1136.
PMID: 33186522
No abstract available.
2.
Jang J, Hajdu C, Liot C, Miller G, Dustin M, Bar-Sagi D
Cell Rep
. 2017 Jul;
20(3):558-571.
PMID: 28723561
Regulatory T (Treg) cell infiltration constitutes a prominent feature of pancreatic ductal adenocarcinoma (PDA). However, the immunomodulatory function of Treg cells in PDA is poorly understood. Here, we demonstrate that...
3.
Choi S, Woo J, Jang Y, Kang J, Jang J, Yi T, et al.
Lab Anim Res
. 2016 Oct;
32(3):151-159.
PMID: 27729931
Inflammatory bowel disease is a chronic inflammatory disorder occurring in the gastrointestinal track. However, the efficacy of current therapeutic strategies has been limited and accompanied by side effects. In order...
4.
Daley D, Zambirinis C, Seifert L, Akkad N, Mohan N, Werba G, et al.
Cell
. 2016 Aug;
166(6):1485-1499.e15.
PMID: 27569912
Inflammation is paramount in pancreatic oncogenesis. We identified a uniquely activated γδT cell population, which constituted ∼40% of tumor-infiltrating T cells in human pancreatic ductal adenocarcinoma (PDA). Recruitment and activation...
5.
Chen G, Chang J, Zhang D, Pinho S, Jang J, Frenette P
Exp Hematol
. 2016 Jul;
44(10):940-6.
PMID: 27393574
Vaso-occlusive crisis (VOC) is one of the most common complications of sickle cell disease (SCD). Recurrent episodes of VOC may cause irreversible organ damage and early mortality in patients with...
6.
Zhang D, Chen G, Manwani D, Mortha A, Xu C, Faith J, et al.
Nature
. 2015 Sep;
525(7570):528-32.
PMID: 26374999
Blood polymorphonuclear neutrophils provide immune protection against pathogens, but may also promote tissue injury in inflammatory diseases. Although neutrophils are generally considered to be a relatively homogeneous population, evidence for...
7.
Waite J, Vardhana S, Shaw P, Jang J, Mccarl C, Cameron T, et al.
Eur J Immunol
. 2013 Aug;
43(12):3343-54.
PMID: 23939929
Entry of lymphocytes into secondary lymphoid organs (SLOs) involves intravascular arrest and intracellular calcium ion ([Ca(2+)]i) elevation. TCR activation triggers increased [Ca(2+)]i and can arrest T-cell motility in vitro. However,...
8.
Scheiermann C, Kunisaki Y, Lucas D, Chow A, Jang J, Zhang D, et al.
Immunity
. 2012 Aug;
37(2):290-301.
PMID: 22863835
The multistep sequence leading to leukocyte migration is thought to be locally regulated at the inflammatory site. Here, we show that broad systemic programs involving long-range signals from the sympathetic...
9.
Almeida C, Scheiermann C, Jang J, Prophete C, Costa F, Conran N, et al.
Blood
. 2012 Jul;
120(14):2879-88.
PMID: 22833547
Inhibition of leukocyte adhesion to the vascular endothelium represents a novel and important approach for decreasing sickle cell disease (SCD) vaso-occlusion. Using a humanized SCD-mouse-model of tumor necrosis factor-α-induced acute...
10.
Jang J, Hidalgo A, Frenette P
Circ Res
. 2012 Mar;
110(8):1057-66.
PMID: 22415018
Rationale: Intravascular neutrophil recruitment and activation are key pathogenic factors that contribute to vascular injury. Intravenous immunoglobulin (IVIG) has been shown to have a beneficial effect in systemic inflammatory disorders;...