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Jun Noguchi

Explore the profile of Jun Noguchi including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 2172
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Recent Articles
1.
Noguchi J, Watanabe S, Oga T, Isoda R, Nakagaki K, Sakai K, et al.
Commun Biol . 2024 May; 7(1):642. PMID: 38802535
Alterations in the experience-dependent and autonomous elaboration of neural circuits are assumed to underlie autism spectrum disorder (ASD), though it is unclear what synaptic traits are responsible. Here, utilizing a...
2.
Horiguchi A, Arakawa Y, Noguchi J, Mori M, Oshima K, Iwama I, et al.
Pediatr Blood Cancer . 2022 Apr; 69(11):e29708. PMID: 35441453
No abstract available.
3.
Ucar H, Watanabe S, Noguchi J, Morimoto Y, Iino Y, Yagishita S, et al.
Nature . 2021 Nov; 600(7890):686-689. PMID: 34819666
Synaptic transmission involves cell-to-cell communication at the synaptic junction between two neurons, and chemical and electrical forms of this process have been extensively studied. In the brain, excitatory glutamatergic synapses...
4.
Inoue K, Arakawa Y, Noguchi J, Irikura T, Watakabe M, Hiraki T, et al.
Pediatr Blood Cancer . 2021 Oct; 69(1):e29380. PMID: 34665512
Perioperative management of severe congenital protein C deficiency remains unestablished. This deficiency is often treated with anticoagulants, such as warfarin. Although anticoagulants need to be perioperatively discontinued, there are few...
5.
Watanabe S, Kurotani T, Oga T, Noguchi J, Isoda R, Nakagami A, et al.
Nat Commun . 2021 Sep; 12(1):5388. PMID: 34526497
Autism spectrum disorder (ASD) is a multifactorial disorder with characteristic synaptic and gene expression changes. Early intervention during childhood is thought to benefit prognosis. Here, we examined the changes in...
6.
Tamura A, Inoue S, Mori T, Noguchi J, Nakamura S, Saito A, et al.
Front Oncol . 2020 Oct; 10:572413. PMID: 33123478
Despite the growing evidences that immune dysfunction contributes to tumor progression, the prognostic value in patients with neuroblastoma regarding circulating immune blood cell counts has not been well characterized. To...
7.
Fukuoka K, Tsumura Y, Noguchi J, Sugawa M, Takaki T, Hiraki T, et al.
Rinsho Ketsueki . 2020 May; 61(4):322-326. PMID: 32378574
Gilteritinib is an FMS-like tyrosine kinase 3 (FLT3) inhibitor that has shown efficacy in patients with refractory or recurrent adult acute myeloid leukemia (AML) with FLT3 mutations. However, there are...
8.
Noguchi J, Nagaoka A, Hayama T, Ucar H, Yagishita S, Takahashi N, et al.
Sci Rep . 2019 Sep; 9(1):13922. PMID: 31558759
Most excitatory synapses in the brain form on dendritic spines. Two-photon uncaging of glutamate is widely utilized to characterize the structural plasticity of dendritic spines in brain slice preparations in...
9.
Noguchi J, Kanno H, Chiba Y, Ito E, Ishiguro A
Pediatr Int . 2017 Jul; 59(7):838-840. PMID: 28745457
No abstract available.
10.
Noguchi J, Hayama T, Watanabe S, Ucar H, Yagishita S, Takahashi N, et al.
Sci Rep . 2016 Sep; 6:32897. PMID: 27595610
Dendritic spines are the postsynaptic sites of most excitatory synapses in the brain, and spine enlargement and shrinkage give rise to long-term potentiation and depression of synapses, respectively. Because spine...