Jun Hyoung Park
Overview
Explore the profile of Jun Hyoung Park including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
853
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0
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Recent Articles
1.
Samanta T, Park J, Kaipparettu B
Cancers (Basel)
. 2025 Mar;
17(5).
PMID: 40075691
Background: Metabolic disorders and chronic liver disease (CLD) play crucial roles in the development and progression of liver cancer (LC). Since the ethnic minority population increasingly suffers from CLD and...
2.
Park J, Jung K, Jia D, Yang S, Attri K, Ahn S, et al.
Cell Rep Med
. 2025 Feb;
6(2):101941.
PMID: 39933530
The biguanide metformin attenuates mitochondrial oxidation and is proposed as an anti-cancer therapy. However, recent clinical studies suggest increased proliferation and fatty acid β-oxidation (FAO) in a subgroup of patients...
3.
Kami Reddy K, Piyarathna D, Park J, Putluri V, Amara C, Kamal A, et al.
JCI Insight
. 2024 Sep;
9(17).
PMID: 39253977
Bladder cancer (BLCA) mortality is higher in African American (AA) patients compared with European American (EA) patients, but the molecular mechanism underlying race-specific differences are unknown. To address this gap,...
4.
Dutta D, Hoque A, Paul B, Park J, Chowdhury C, Quadir M, et al.
J Biomed Sci
. 2024 Aug;
31(1):81.
PMID: 39164686
Background: Betulinic acid (BA) has been well investigated for its antiproliferative and mitochondrial pathway-mediated apoptosis-inducing effects on various cancers. However, its poor solubility and off-target activity have limited its utility...
5.
Oturkar C, Rosario S, Hutson A, Groman A, Edge S, Morrison C, et al.
iScience
. 2024 Jun;
27(6):109995.
PMID: 38868185
The canonical mechanism behind tamoxifen's therapeutic effect on estrogen receptor α/ESR1+ breast cancers is inhibition of ESR1-dependent estrogen signaling. Although ESR1+ tumors expressing wild-type p53 were reported to be more...
6.
Murthy D, Dutta D, Attri K, Samanta T, Yang S, Jung K, et al.
Cancer Lett
. 2024 Feb;
587:216724.
PMID: 38373689
CD24 is a well-characterized breast cancer (BC) stem cell (BCSC) marker. Primary breast tumor cells having CD24-negativity together with CD44-positivity is known to maintain high metastatic potential. However, the functional...
7.
Ahn S, Park J, Grimm S, Piyarathna D, Samanta T, Putluri V, et al.
Cancer Res
. 2023 Oct;
84(2):291-304.
PMID: 37906431
Significance: Increased fatty acid oxidation induced by endocrine therapy activates Src signaling to promote endocrine resistance in breast cancer, which can be overcome using clinically approved therapies targeting FAO and...
8.
Dutta D, Kanca O, Byeon S, Marcogliese P, Zuo Z, Shridharan R, et al.
Nat Metab
. 2023 Aug;
5(9):1595-1614.
PMID: 37653044
In most eukaryotic cells, fatty acid synthesis (FAS) occurs in the cytoplasm and in mitochondria. However, the relative contribution of mitochondrial FAS (mtFAS) to the cellular lipidome is not well...
9.
Masschelin P, Saha P, Ochsner S, Cox A, Kim K, Felix J, et al.
Elife
. 2023 Jul;
12.
PMID: 37417957
Flavin adenine dinucleotide (FAD) interacts with flavoproteins to mediate oxidation-reduction reactions required for cellular energy demands. Not surprisingly, mutations that alter FAD binding to flavoproteins cause rare inborn errors of...
10.
Hong S, Kang J, Park J, Park H, Kim E
Health Informatics J
. 2023 Mar;
29(1):14604582231169297.
PMID: 36995242
This study aimed to evaluate the quality and readability of web pages providing information about hand osteoarthritis using several authorized methods. A web page exploration was performed using the Google...