Jun-An Ma
Overview
Explore the profile of Jun-An Ma including associated specialties, affiliations and a list of published articles.
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Articles
132
Citations
833
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Recent Articles
1.
Liu C, Yang Y, Hong W, Ma J, Zhu Y
Angew Chem Int Ed Engl
. 2024 Dec;
64(6):e202417827.
PMID: 39714434
Asymmetric synthesis relies on seamless transmission of stereochemical information from a chiral reagent/catalyst to a prochiral substrate. The disruption by substrates' structural changes presents a hurdle in innovating generality-oriented asymmetric...
2.
Zhou T, Zhang Z, Nie J, Kwong F, Ma J, Cheung C
Nat Commun
. 2024 Nov;
15(1):9926.
PMID: 39548078
The integration of trifluoromethyl groups and three-dimensional quaternary carbon moieties into organic molecules has emerged as a prominent strategy in medicinal chemistry to augment drug efficacy. Although trifluoromethyl (hetero)aromatic amines...
3.
Poper W, Ma J, Jasinski M
J Org Chem
. 2024 Sep;
89(20):15331-15335.
PMID: 39347623
Readily available 2-unsubstituted imidazole -oxides were examined as starting materials for the preparation of fully substituted 1,4,5-aryl/alkyl 2-trifluoromethylsulfanyl-imidazoles. Whereas activation of the -oxide function followed by attempted nucleophilic addition of...
4.
Zeng H, Yin R, Zhao Y, Ma J, Wu J
Nat Chem
. 2024 Sep;
16(11):1822-1830.
PMID: 39333390
Alkenes serve as versatile building blocks in diverse organic transformations. Despite notable advancements in olefination methods, a general strategy for the direct conversion of carboxylic acids, alcohols and alkanes into...
5.
Zhang Y, Song K, Wang T, Wu S, Xu G, Liao S, et al.
J Org Chem
. 2024 Aug;
89(17):12044-12048.
PMID: 39180535
Motivated by the success of 9,9'-spirobifluorene () in optoelectronic materials, we synthesized a novel spiro compound, spirophenanthrene (). Incorporating a phenanthrene unit as the core, we aimed to leverage the...
6.
Li Y, Su Y, Wang H, Xie Y, Wang X, Chang L, et al.
J Am Chem Soc
. 2024 Aug;
146(39):26884-26896.
PMID: 39164893
Monosubstituted tetrazines are important bioorthogonal reactive tools due to their rapid ligation with -cyclooctene. However, their application is limited by the reactivity-stability paradox in biological environments. In this study, we...
7.
Sun Z, Li H, Gao J, Xing Y, Liu Y, Jin C, et al.
Langmuir
. 2024 Aug;
40(33):17454-17462.
PMID: 39101658
In nature, selective interactions between chiral amino acids and crystals are important for the formation of chiral biominerals and provide insight into the mysterious origin of homochirality. Here, we show...
8.
Li S, Zhang X, Mei Z, Liu Y, Ma J, Zhang F
J Am Chem Soc
. 2024 Jul;
146(29):19962-19973.
PMID: 38985576
Installing fluorine atoms onto natural products holds great promise for the generation of fluorinated molecules with improved or novel pharmacological properties. The enzymatic oxidative carbon-carbon coupling reaction represents a straightforward...
9.
Marie N, Ma J, Tognetti V, Cahard D
Angew Chem Int Ed Engl
. 2024 Jun;
63(34):e202407689.
PMID: 38845586
A photocatalyzed formal (3+2) cycloaddition has been developed to construct original polysubstituted α-SCF cyclopentanones in a regio- and diastereoselective manner. This building block approach leverages trifluoromethylthio alkynes and branched/linear aldehydes,...
10.
Li X, Zhang F, Ma J, Liu Y
Phys Chem Chem Phys
. 2024 Apr;
26(16):12331-12344.
PMID: 38598177
Oxaloacetic acid (OAA) is a β-ketocarboxylic acid, which plays an important role as an intermediate in some metabolic pathways, including the tricarboxylic acid cycle, gluconeogenesis and fatty acid biosynthesis. Animal...