Julius L Decano
Overview
Explore the profile of Julius L Decano including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
315
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Recent Articles
1.
Halu A, Chelvanambi S, Decano J, Matamalas J, Whelan M, Asano T, et al.
Genome Med
. 2025 Jan;
17(1):7.
PMID: 39833831
Background: Large-scale pharmacogenomic resources, such as the Connectivity Map (CMap), have greatly assisted computational drug discovery. However, despite their widespread use, CMap-based methods have thus far been agnostic to the...
2.
Kip P, Sluiter T, MacArthur M, Tao M, Kruit N, Mitchell S, et al.
Nat Commun
. 2024 Nov;
15(1):9652.
PMID: 39511181
Short-term preoperative methionine restriction (MetR) is a promising translatable strategy to mitigate surgical injury response. However, its application to improve post-interventional vascular remodeling remains underexplored. Here we find that MetR...
3.
Chelvanambi S, Decano J, Winkels H, Giannarelli C, Aikawa M
Arterioscler Thromb Vasc Biol
. 2024 Oct;
44(11):2253-2257.
PMID: 39441912
No abstract available.
4.
Matamalas J, Chelvanambi S, Decano J, Franca R, Halu A, Santinelli-Pestana D, et al.
PNAS Nexus
. 2024 Aug;
3(8):pgae294.
PMID: 39192848
The coronavirus disease (COVID-19) pandemic has occurred in Massachusetts in multiple waves led by a series of emerging variants. While the evidence has linked obesity with severe symptoms of COVID-19,...
5.
Decano J, Maiorino E, Matamalas J, Chelvanambi S, Tiemeijer B, Yanagihara Y, et al.
Circulation
. 2023 Oct;
148(19):1459-1478.
PMID: 37850387
Background: Interferon-γ (IFNγ) signaling plays a complex role in atherogenesis. IFNγ stimulation of macrophages permits in vitro exploration of proinflammatory mechanisms and the development of novel immune therapies. We hypothesized...
6.
Herrera V, Gromisch C, Decano J, Pasion K, Tan G, Hua N, et al.
Sci Rep
. 2023 Feb;
13(1):2703.
PMID: 36792616
Progressive secondary brain injury-induced by dysregulated neuroinflammation in spontaneous intracerebral hemorrhage (sICH)-underlies high sICH-mortality and remains without FDA-approved pharmacotherapy. Clinical insight that hematoma-directed interventions do not improve mortality prioritizes resolving...
7.
Whitaker R, Decano J, Gormley C, Beigie C, Meisel C, Tan G, et al.
Theranostics
. 2022 Dec;
12(18):7646-7667.
PMID: 36451861
High mortality in pancreatic cancer (PDAC) and triple negative breast cancer (TNBC) highlight the need to capitalize on nanoscale-design advantages for multifunctional diagnostics and therapies. DNA/RNA-therapies can provide potential breakthroughs,...
8.
Katsuki S, Jha P, Lupieri A, Nakano T, S A Passos L, Rogers M, et al.
Circ Res
. 2022 Oct;
131(11):873-889.
PMID: 36263780
Background: Activated macrophages contribute to the pathogenesis of vascular disease. Vein graft failure is a major clinical problem with limited therapeutic options. PCSK9 (proprotein convertase subtilisin/kexin 9) increases low-density lipoprotein...
9.
Decano J, Aikawa M, Singh S
Arterioscler Thromb Vasc Biol
. 2022 May;
42(7):865-867.
PMID: 35616034
No abstract available.
10.
Decano J, Iwamoto Y, Goto S, Lee J, Matamalas J, Halu A, et al.
Cell Rep
. 2022 Apr;
39(2):110685.
PMID: 35417712
Cellular heterogeneity of aortic valves complicates the mechanistic evaluation of the calcification processes in calcific aortic valve disease (CAVD), and animal disease models are lacking. In this study, we identify...