Juliet M Mwirigi
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Explore the profile of Juliet M Mwirigi including associated specialties, affiliations and a list of published articles.
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20
Citations
89
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Recent Articles
1.
Franco-Enzastiga U, Inturi N, Natarajan K, Mwirigi J, Mazhar K, Schlachetzki J, et al.
Pain
. 2025 Feb;
166(3):614-630.
PMID: 39928726
Cell states are influenced by the regulation of gene expression orchestrated by transcription factors capable of binding to accessible DNA regions. To uncover if sex differences exist in chromatin accessibility...
2.
Sankaranarayanan I, Kume M, Mohammed A, Mwirigi J, Inturi N, Munro G, et al.
Pain
. 2025 Jan;
PMID: 39878635
Hyperalgesic priming is a model system that has been widely used to understand plasticity in painful stimulus-detecting sensory neurons, called nociceptors. A key feature of this model system is that...
3.
Leong T, Gao Z, David E, Li X, Cai Q, Mwirigi J, et al.
ACS Nano
. 2024 Dec;
18(51):34720-34729.
PMID: 39655357
The blood-spinal cord barrier (BSCB) tightly regulates the transport of molecules from the blood to the spinal cord. Herein, we present an approach for transient modulation of BSCB permeability and...
4.
Lacagnina M, Willcox K, Boukelmoune N, Bavencoffe A, Sankaranarayanan I, Barratt D, et al.
Sci Transl Med
. 2024 Sep;
16(766):eadj1277.
PMID: 39321269
Neuroimmune interactions are essential for the development of neuropathic pain, yet the contributions of distinct immune cell populations have not been fully unraveled. Here, we demonstrate the critical role of...
5.
Mitchell M, Torrijos G, Cook L, Mwirigi J, He L, Shiers S, et al.
Neurobiol Pain
. 2024 Aug;
16:100159.
PMID: 39156884
Plasticity of dorsal root ganglion (DRG) nociceptors in the peripheral nervous system requires new protein synthesis. This plasticity is believed to be responsible for the physiological changes seen in DRG...
6.
Sankaranarayanan I, Kume M, Mohammed A, Mwirigi J, Inturi N, Munro G, et al.
bioRxiv
. 2024 Aug;
PMID: 39149295
Hyperalgesic priming is a model system that has been widely used to understand plasticity in painful stimulus-detecting sensory neurons, called nociceptors. A key feature of this model system is that...
7.
Li Y, Uhelski M, North R, Mwirigi J, Tatsui C, McDonough K, et al.
Brain
. 2024 Jul;
147(9):2991-2997.
PMID: 39046204
Spontaneous activity in dorsal root ganglion (DRG) neurons is a key driver of neuropathic pain in patients suffering from this largely untreated disease. While many intracellular signalling mechanisms have been...
8.
Ferreira D, Shen B, Mwirigi J, Shiers S, Sankaranarayanan I, Kotamarti M, et al.
bioRxiv
. 2024 Jun;
PMID: 38915676
Diabetic peripheral neuropathy (DPN) is a prevalent complication of diabetes mellitus that is caused by metabolic toxicity to peripheral axons. We aimed to gain deep mechanistic insight into the disease...
9.
Bhuiyan S, Xu M, Yang L, Semizoglou E, Bhatia P, Pantaleo K, et al.
Sci Adv
. 2024 Jun;
10(25):eadj9173.
PMID: 38905344
Sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are specialized to detect and transduce diverse environmental stimuli to the central nervous system. Single-cell RNA sequencing has...
10.
Xu M, Thottappillil N, Cherief M, Li Z, Zhu M, Xing X, et al.
bioRxiv
. 2024 Jun;
PMID: 38895367
The profound pain accompanying bone fracture is mediated by somatosensory neurons, which also appear to be required to initiate bone regeneration following fracture. Surprisingly, the precise neuroanatomical circuitry mediating skeletal...