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Julien Rougeot

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Articles 11
Citations 191
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Recent Articles
1.
Rougeot J, Torraca V, Zakrzewska A, Kanwal Z, Jansen H, Sommer F, et al.
Front Immunol . 2019 Dec; 10:2720. PMID: 31832066
[This corrects the article DOI: 10.3389/fimmu.2019.00832.].
2.
Rougeot J, Chrispijn N, Aben M, Elurbe D, Andralojc K, Murphy P, et al.
Development . 2019 Sep; 146(19). PMID: 31488564
Polycomb group (PcG) proteins are transcriptional repressors that are important regulators of cell fate during embryonic development. Among them, Ezh2 is responsible for catalyzing the epigenetic repressive mark H3K27me3 and...
3.
Rougeot J, Torraca V, Zakrzewska A, Kanwal Z, Jansen H, Sommer F, et al.
Front Immunol . 2019 May; 10:832. PMID: 31110502
Macrophages are phagocytic cells from the innate immune system, which forms the first line of host defense against invading pathogens. These highly dynamic immune cells can adopt specific functional phenotypes,...
4.
San B, Rougeot J, Voeltzke K, van Vegchel G, Aben M, Andralojc K, et al.
PLoS One . 2019 Jan; 14(1):e0210217. PMID: 30677064
Polycomb group (PcG) proteins are essential regulators of epigenetic gene silencing and development. The PcG protein enhancer of zeste homolog 2 (Ezh2) is a key component of the Polycomb Repressive...
5.
Foulkes M, Henry K, Rougeot J, Hooper-Greenhill E, Loynes C, Jeffrey P, et al.
Sci Rep . 2017 Jul; 7(1):4967. PMID: 28694436
There remains a need to identify novel pro-resolution drugs for treatment of inflammatory disease. To date, there are no neutrophil-specific anti-inflammatory treatments in clinical use, perhaps due to our lack...
6.
Benard E, Racz P, Rougeot J, Nezhinsky A, Verbeek F, Spaink H, et al.
J Innate Immun . 2014 Sep; 7(2):136-52. PMID: 25247677
Macrophage-expressed gene 1 (MPEG1) encodes an evolutionarily conserved protein with a predicted membrane attack complex/perforin domain associated with host defence against invading pathogens. In vertebrates, MPEG1/perforin-2 is an integral membrane...
7.
Rougeot J, Zakrzewska A, Kanwal Z, Jansen H, Spaink H, Meijer A
Methods Mol Biol . 2014 Aug; 1197:261-74. PMID: 25172286
The zebrafish (Danio rerio) is increasingly used as a model for studying infectious diseases. This nonmammalian vertebrate host, which is transparent at the early life stages, is especially attractive for...
8.
Rougeot J, Renard M, Randsholt N, Peronnet F, Mouchel-Vielh E
PLoS One . 2013 Nov; 8(10):e77592. PMID: 24204884
Drosophila wings mainly consist of two cell types, vein and intervein cells. Acquisition of either fate depends on specific expression of genes that are controlled by several signaling pathways. The...
9.
Ordas A, Kanwal Z, Lindenberg V, Rougeot J, Mink M, Spaink H, et al.
BMC Genomics . 2013 Oct; 14:696. PMID: 24112639
Background: MicroRNAs (miRNAs) have recently been shown to play important roles in development of the immune system and in fine-tuning of immune responses. Human miR-146 family members are known as...
10.
Coleno-Costes A, Jang S, de Vanssay A, Rougeot J, Bouceba T, Randsholt N, et al.
PLoS Genet . 2012 Oct; 8(10):e1003006. PMID: 23071455
Chromodomains are found in many regulators of chromatin structure, and most of them recognize methylated lysines on histones. Here, we investigate the role of the Drosophila melanogaster protein Corto's chromodomain....