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Julien Leclercq

Explore the profile of Julien Leclercq including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 63
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Recent Articles
11.
Mendonca T, Bienboire-Frosini C, Kowalczyk I, Leclercq J, Arroub S, Pageat P
Animals (Basel) . 2019 Jun; 9(6). PMID: 31146422
The learning and cognitive challenges that horses may face differ according to the activities in which they are involved. The aim of this investigation was to study the influence of...
12.
Segaoula Z, Leclercq J, Verones V, Flouquet N, Lecoeur M, Ach L, et al.
J Med Chem . 2016 Aug; 59(18):8422-40. PMID: 27538123
Benzopyridothiadiazepine (2a) and benzopyridooxathiazepine (2b) were modified to produce tricyclic quinazolinone 15-18 or benzothiadiazine 26-27 derivatives. These compounds were evaluated in cytotoxicity and tubulin inhibition assays and led to potent...
13.
Driowya M, Leclercq J, Verones V, Barczyk A, Lecoeur M, Renault N, et al.
Eur J Med Chem . 2016 Apr; 115:393-405. PMID: 27031215
A series of 1-phenyl-[1,2,4]triazolo[4,3-a]quinazolin-5-ones designed as conformationally restricted CA-4 analogues, were tested for their tubulin polymerization and growth inhibitory activities. The 3-hydroxy-4-methoxy derivatives 11d and 12d are potent inhibitors of...