Julie C Mitchell
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Explore the profile of Julie C Mitchell including associated specialties, affiliations and a list of published articles.
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47
Citations
900
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Recent Articles
1.
Glukhov E, Kalitin D, Stepanenko D, Zhu Y, Nguyen T, Jones G, et al.
Biophys J
. 2024 May;
123(17):2902-2909.
PMID: 38751115
The precise prediction of major histocompatibility complex (MHC)-peptide complex structures is pivotal for understanding cellular immune responses and advancing vaccine design. In this study, we enhanced AlphaFold's capabilities by fine-tuning...
2.
Satalkar V, Degaga G, Li W, Pang Y, McShan A, Gumbart J, et al.
Biophys J
. 2024 Feb;
123(17):2790-2806.
PMID: 38297834
De novo peptide design is a new frontier that has broad application potential in the biological and biomedical fields. Most existing models for de novo peptide design are largely based...
3.
Glukhov E, Kalitin D, Stepanenko D, Zhu Y, Nguyen T, Jones G, et al.
bioRxiv
. 2023 Dec;
PMID: 38077000
The precise prediction of Major Histocompatibility Complex (MHC)-peptide complex structures is pivotal for understanding cellular immune responses and advancing vaccine design. In this study, we enhanced AlphaFold's capabilities by fine-tuning...
4.
Liu Y, Yuan G, Hassan M, Abraham P, Mitchell J, Jacobson D, et al.
Biodes Res
. 2023 Oct;
2022:9863496.
PMID: 37850147
Plants adapt to their changing environments by sensing and responding to physical, biological, and chemical stimuli. Due to their sessile lifestyles, plants experience a vast array of external stimuli and...
5.
Yang X, Liu D, Lu H, Weston D, Chen J, Muchero W, et al.
Biodes Res
. 2023 Oct;
2021:9798714.
PMID: 37849951
A grand challenge facing society is climate change caused mainly by rising CO concentration in Earth's atmosphere. Terrestrial plants are linchpins in global carbon cycling, with a unique capability of...
6.
Yang X, Medford J, Markel K, Shih P, De Paoli H, Trinh C, et al.
Biodes Res
. 2023 Oct;
2020:8051764.
PMID: 37849899
Human life intimately depends on plants for food, biomaterials, health, energy, and a sustainable environment. Various plants have been genetically improved mostly through breeding, along with limited modification via genetic...
7.
Chen S, Hassan M, Jernigan R, Jia K, Kihara D, Kloczkowski A, et al.
Proc Natl Acad Sci U S A
. 2022 Dec;
120(1):e2214423119.
PMID: 36580595
No abstract available.
8.
Hameedi M, Prates E, Garvin M, Mathews I, Amos B, Demerdash O, et al.
Nat Commun
. 2022 Sep;
13(1):5285.
PMID: 36075915
In addition to its essential role in viral polyprotein processing, the SARS-CoV-2 3C-like protease (3CLpro) can cleave human immune signaling proteins, like NF-κB Essential Modulator (NEMO) and deregulate the host...
9.
Liu S, Xiao Z, Mishra S, Mitchell J, Smith J, Quarles L, et al.
J Chem Inf Model
. 2022 Jul;
62(15):3627-3637.
PMID: 35868851
Fibroblast growth factor 23 (FGF23) is a therapeutic target for treating hereditary and acquired hypophosphatemic disorders, such as X-linked hypophosphatemic (XLH) rickets and tumor-induced osteomalacia (TIO), respectively. FGF23-induced hypophosphatemia is...
10.
Davidson R, Woods J, Effler T, Thavappiragasam M, Mitchell J, Parks J, et al.
Bioinformatics
. 2022 May;
38(12):3297-3298.
PMID: 35512391
Summary: Easy-to-use, open-source, general-purpose programs for modeling a protein structure from inter-atomic distances are needed for modeling from experimental data and refinement of predicted protein structures. OpenMDlr is an open-source...