Julie Borland
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    Explore the profile of Julie Borland including associated specialties, affiliations and a list of published articles.
          
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              Articles
              30
            
            
              Citations
              725
            
            
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  Recent Articles
          1.
        
    
    Song I, Zong J, Borland J, Jerva F, Wynne B, Zamek-Gliszczynski M, et al.
  
  
    J Acquir Immune Defic Syndr
    . 2016 Mar;
          72(4):400-7.
    
    PMID: 26974526
  
  
          Background: Dolutegravir is an integrase strand transfer inhibitor (INSTI) licensed for use in HIV-1 infection and is an inhibitor of organic cation transporter 2 (OCT2). This study assessed the effect...
      
2.
        
    
    Song I, Weller S, Patel J, Borland J, Wynne B, Choukour M, et al.
  
  
    Eur J Clin Pharmacol
    . 2016 Feb;
          72(6):665-70.
    
    PMID: 26898568
  
  
          Purpose: Dolutegravir (DTG) is primarily metabolized by UGT1A1 with CYP3A as a minor route. Carbamazepine (CBZ) is a potent inducer of these enzymes; thus, the effect of oral extended-release CBZ...
      
3.
        
    
    Song I, Borland J, Savina P, Chen S, Patel P, Wajima T, et al.
  
  
    Clin Pharmacol Drug Dev
    . 2015 Jun;
          2(4):342-348.
    
    PMID: 26097786
  
  
          This study evaluated dolutegravir pharmacokinetics (PK) in subjects with moderate hepatic impairment compared to matched, healthy controls. In this open-label, parallel-group study, eight adult subjects with moderate hepatic impairment (Child-Pugh...
      
4.
        
    
    Song I, Borland J, Chen S, Wajima T, Peppercorn A, Piscitelli S
  
  
    Ann Pharmacother
    . 2015 Apr;
          49(7):784-9.
    
    PMID: 25862012
  
  
          Background: Dolutegravir (DTG; Tivicay; ViiV Healthcare, Research Triangle Park, NC) is an HIV-1-unboosted integrase inhibitor with no cytochrome P450 or uridine 5'diphosphate-glucuronosyltransferase inhibition or induction. As DTG is administered to...
      
5.
        
    
    Song I, Borland J, Arya N, Wynne B, Piscitelli S
  
  
    J Clin Pharmacol
    . 2014 Dec;
          55(5):490-6.
    
    PMID: 25449994
  
  
          All commercially available integrase inhibitors are 2-metal binders and may be affected by co-administration with metal cations. The purpose of this study was to evaluate the effect of calcium and...
      
6.
        
    
    Zong J, Borland J, Jerva F, Wynne B, Choukour M, Song I
  
  
    J Int AIDS Soc
    . 2014 Nov;
          17(4 Suppl 3):19584.
    
    PMID: 25394090
  
  
          Introduction: Dolutegravir (DTG) is an HIV integrase strand transfer inhibitor approved for use in combination with other antiretrovirals for the treatment of HIV-infection in adults and adolescents. Metformin is a...
      
7.
        
    
    Song I, Borland J, Chen S, Peppercorn A, Wajima T, Piscitelli S
  
  
    Antimicrob Agents Chemother
    . 2014 Aug;
          58(11):6696-700.
    
    PMID: 25155604
  
  
          Dolutegravir (DTG) is an HIV integrase inhibitor (INI) with demonstrated activity in INI-naive and INI-resistant patients. The objective of this open-label, 2-period, single-sequence study was to evaluate the effect of...
      
8.
        
    
    Song I, Borland J, Chen S, Guta P, Lou Y, Wilfret D, et al.
  
  
    Eur J Clin Pharmacol
    . 2014 Aug;
          70(10):1173-9.
    
    PMID: 25146692
  
  
          Purpose: Dolutegravir (DTG) is an unboosted, integrase inhibitor for the treatment of HIV infection. Two studies evaluated the effects of efavirenz (EFV) and tipranavir/ritonavir (TPV/r) on DTG pharmacokinetics (PK) in...
      
9.
        
    
    Johnson M, Borland J, Chen S, Savina P, Wynne B, Piscitelli S
  
  
    Br J Clin Pharmacol
    . 2014 May;
          78(5):1043-9.
    
    PMID: 24838177
  
  
          Aims: The aim was to evaluate the effect of boceprevir and telaprevir on dolutegravir pharmacokinetics (PK); the effect of dolutegravir on boceprevir and telaprevir PK was assessed through comparison with...
      
10.
        
    
    Weller S, Chen S, Borland J, Savina P, Wynne B, Piscitelli S
  
  
    J Acquir Immune Defic Syndr
    . 2014 May;
          66(4):393-8.
    
    PMID: 24798770
  
  
          Background: The integrase inhibitor dolutegravir and nucleoside analogues abacavir and lamivudine are once-daily treatment options for HIV. This study (NCT01622790) evaluated, first, the bioequivalence (BE) of a fixed-dose combination (FDC)...