Julian A Schardt
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Explore the profile of Julian A Schardt including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
259
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Recent Articles
1.
Schardt J, Keller M, Seipel K, Pabst T
Biochim Biophys Acta
. 2015 Jul;
1849(9):1188-97.
PMID: 26162987
Calreticulin (CALR) is a highly conserved, multifunctional protein involved in a variety of cellular processes including the maintenance of intracellular calcium homeostasis, proper protein folding, differentiation and immunogenic cell death....
2.
Schardt J, Mueller B, Pabst T
Methods Enzymol
. 2011 Jan;
489:227-43.
PMID: 21266233
There is accumulating evidence for the involvement of the unfolded protein response (UPR) in the pathogenesis of many tumor types in humans. This is particularly the case in rapidly growing...
3.
Frese-Schaper M, Schardt J, Sakai T, Carboni G, Schmid R, Frese S
FEBS Lett
. 2010 May;
584(13):2867-71.
PMID: 20450916
Tissue transglutaminase (TG2) is implicated in cellular processes such as apoptosis and cell migration. Its acyl transferase activity cross-links certain proteins, among them transcription factors were described. We show here...
4.
Eyholzer M, Schmid S, Schardt J, Haefliger S, Mueller B, Pabst T
Leuk Res
. 2009 Dec;
34(5):672-6.
PMID: 20018373
microRNA-223 (miR-223) can trigger normal granulopoiesis. miR-223 expression is regulated by two distinct CEBPA (CCAAT/enhancer binding protein-alpha) sites. Here, we report that miR-223 is largely suppressed in cells from acute...
5.
Schardt J, Eyholzer M, Timchenko N, Mueller B, Pabst T
J Cell Mol Med
. 2009 Aug;
14(6B):1509-19.
PMID: 19659458
The unfolded protein response (UPR) is triggered by the accumulation of misfolded proteins within the endoplasmic reticulum (ER). The role of the UPR during leukemogenesis is unknown so far. Here,...
6.
Schardt J, Weber D, Eyholzer M, Mueller B, Pabst T
Clin Cancer Res
. 2009 May;
15(11):3834-41.
PMID: 19470730
Purpose: The unfolded protein response is triggered by the accumulation of misfolded proteins within the endoplasmic reticulum. Previous studies suggest that the unfolded protein response is activated in some cancer...
7.
Schardt J, Meyer M, Hartmann C, Schubert F, Schmidt-Kittler O, Fuhrmann C, et al.
Cancer Cell
. 2005 Sep;
8(3):227-39.
PMID: 16169467
Chromosomal instability in human breast cancer is known to take place before mammary neoplasias display morphological signs of invasion. We describe here the unexpected finding of a tumor cell population...
8.
Stoecklein N, Erbersdobler A, Schmidt-Kittler O, Diebold J, Schardt J, Izbicki J, et al.
Am J Pathol
. 2002 Jul;
161(1):43-51.
PMID: 12107088
Global genome amplification from formalin-fixed tissues is still problematic when performed with low cell numbers. Here, we tested a recently developed method for whole genome amplification termed "SCOMP" (single cell...