Julia van der Hoven
Overview
Explore the profile of Julia van der Hoven including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
500
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ariawan D, van der Hoven J, Morey N, Pushpitha K, Genoud S, Stefen H, et al.
J Med Chem
. 2024 Dec;
68(5):5211-5221.
PMID: 39630561
Cyclotides are naturally occurring cyclic peptides with three disulfide bonds, offering remarkable stability. In neurological disorders, the formation of a complex between postsynaptic density protein 95 and NMDA receptors (NMDARs)...
2.
Ariawan D, Thananthirige K, El-Omar A, van der Hoven J, Genoud S, Stefen H, et al.
RSC Adv
. 2024 Oct;
14(47):34637-34642.
PMID: 39479480
Peptide therapeutics are an emerging class of drugs to treat neurodegenerative diseases by inhibiting protein-protein interactions (PPIs). Nerinetide has recently emerged as a promising therapeutic for the treatment of ischemic...
3.
Wong C, Baldelli A, Tietz O, van der Hoven J, Suman J, Ong H, et al.
Int J Pharm
. 2024 Feb;
654:123922.
PMID: 38401871
The surge in neurological disorders necessitates innovative strategies for delivering active pharmaceutical ingredients to the brain. The non-invasive intranasal route has emerged as a promising approach to optimize drug delivery...
4.
Ke Y, van Hummel A, Au C, Chan G, Lee W, van der Hoven J, et al.
Neuron
. 2024 Feb;
112(8):1249-1264.e8.
PMID: 38366598
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are characterized by cytoplasmic deposition of the nuclear TAR-binding protein 43 (TDP-43). Although cytoplasmic re-localization of TDP-43 is a key event in...
5.
van Hummel A, Sabale M, Przybyla M, van der Hoven J, Chan G, Feiten A, et al.
Neuropathol Appl Neurobiol
. 2023 Mar;
49(2):e12902.
PMID: 36951214
Aims: Amyotrophic lateral sclerosis (ALS) is characterised by a progressive loss of upper and lower motor neurons leading to muscle weakness and eventually death. Frontotemporal dementia (FTD) presents clinically with...
6.
Morey N, Przybyla M, van der Hoven J, Ke Y, Delerue F, van Eersel J, et al.
Sci Adv
. 2022 Dec;
8(48):eadd2577.
PMID: 36459557
Hyperphosphorylated microtubule-associated protein tau has been implicated in dementia, epilepsy, and other neurological disorders. In contrast, site-specific phosphorylation of tau at threonine 205 (T205) by the kinase p38γ was shown...
7.
Deng Y, Bi M, Delerue F, Forrest S, Chan G, van der Hoven J, et al.
Acta Neuropathol
. 2022 Jul;
144(4):637-650.
PMID: 35780436
In Alzheimer's disease (AD), where amyloid-β (Aβ) and tau deposits in the brain, hyperexcitation of neuronal networks is an underlying disease mechanism, but its cause remains unclear. Here, we used...
8.
Ippati S, Deng Y, van der Hoven J, Heu C, van Hummel A, Chua S, et al.
Proc Natl Acad Sci U S A
. 2021 Mar;
118(12).
PMID: 33737393
Neurons are postmitotic cells. Reactivation of the cell cycle by neurons has been reported in Alzheimer's disease (AD) brains and models. This gave rise to the hypothesis that reentering the...
9.
van der Hoven J, van Hummel A, Przybyla M, Asih P, Gajwani M, Feiten A, et al.
Sci Rep
. 2020 Aug;
10(1):13845.
PMID: 32796905
Antibodies have been explored extensively as a potential therapeutic for Alzheimer's disease, where amyloid-β (Aβ) peptides and the tau protein deposit in patient brains. While the major focus of antibody-based...
10.
Przybyla M, van Eersel J, van Hummel A, van der Hoven J, Sabale M, Harasta A, et al.
Brain
. 2020 May;
143(6):1889-1904.
PMID: 32375177
Hyperphosphorylation and deposition of tau in the brain characterizes frontotemporal dementia and Alzheimer's disease. Disease-associated mutations in the tau-encoding MAPT gene have enabled the generation of transgenic mouse models that...