Julia Sim
Overview
Explore the profile of Julia Sim including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
19
Citations
1330
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pestronk A, Schmidt R, Bucelli R, Sim J
Neuropathol Appl Neurobiol
. 2023 Mar;
49(2):e12898.
PMID: 36868780
Aims: We examined major protein components of Schwann cells (SCs) and myelin in normal and diseased human peripheral nerves. Methods: We evaluated distributions of neural cell adhesion molecule (NCAM), P0...
2.
Williams J, Manivasagam S, Smith B, Sim J, Vollmer L, Daniels B, et al.
Glia
. 2020 Jan;
68(7):1361-1374.
PMID: 31961459
During multiple sclerosis (MS), an inflammatory and neurodegenerative disease of the central nervous system (CNS), symptoms, and outcomes are determined by the location of inflammatory lesions. While we and others...
3.
Parker Harp C, Archambault A, Sim J, Shlomchik M, Russell J, Wu G
PLoS One
. 2018 Jun;
13(6):e0199694.
PMID: 29944721
Recent success with B cell depletion therapies has revitalized efforts to understand the pathogenic role of B cells in Multiple Sclerosis (MS). Using the adoptive transfer system of experimental autoimmune...
4.
IL-1-induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation
Lin C, Bradstreet T, Schwarzkopf E, Jarjour N, Chou C, Archambault A, et al.
J Exp Med
. 2016 Feb;
213(2):251-71.
PMID: 26834156
The features that define autoreactive T helper (Th) cell pathogenicity remain obscure. We have previously shown that Th cells require the transcription factor Bhlhe40 to mediate experimental autoimmune encephalomyelitis (EAE),...
5.
Parker Harp C, Archambault A, Sim J, Ferris S, Mikesell R, Koni P, et al.
J Immunol
. 2015 Apr;
194(11):5077-84.
PMID: 25895531
B cells are increasingly regarded as integral to the pathogenesis of multiple sclerosis, in part as a result of the success of B cell-depletion therapy. Multiple B cell-dependent mechanisms contributing...
6.
Shin S, Walz K, Archambault A, Sim J, Bollman B, Koenigsknecht-Talboo J, et al.
J Neuroimmunol
. 2014 May;
271(1-2):8-17.
PMID: 24794230
Apolipoprotein E (ApoE) functions as a ligand in receptor-mediated endocytosis of lipoprotein particles and has been demonstrated to play a role in antigen presentation. To explore the contribution of ApoE...
7.
Lin C, Bradstreet T, Schwarzkopf E, Sim J, Carrero J, Chou C, et al.
Nat Commun
. 2014 Apr;
5:3551.
PMID: 24699451
TH1 and TH17 cells mediate neuroinflammation in experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis. Pathogenic TH cells in EAE must produce the pro-inflammatory cytokine granulocyte-macrophage colony stimulating...
8.
Archambault A, Carrero J, Barnett L, McGee N, Sim J, Wright J, et al.
J Immunol
. 2013 Jun;
191(2):545-50.
PMID: 23772037
The activation, differentiation, and subsequent effector functions of CD4 T cells depend on interactions with a multitude of MHC class II (MHCII)-expressing APCs. To evaluate the individual contribution of various...
9.
Edelson B, Bradstreet T, Kc W, Hildner K, Herzog J, Sim J, et al.
PLoS One
. 2011 Nov;
6(10):e25660.
PMID: 22065991
Dendritic cells (DCs) subsets differ in precursor cell of origin, functional properties, requirements for growth factors, and dependence on transcription factors. Lymphoid-tissue resident CD8α(+) conventional DCs (cDCs) and CD11b(low/-)CD103(+) non-lymphoid...
10.
Graham D, Akilesh H, Gmyrek G, Piccio L, Gilfillan S, Sim J, et al.
Blood
. 2010 Jul;
116(17):3208-18.
PMID: 20634378
Immature dendritic cells (DCs) specialize in antigen capture and maintain a highly dynamic pool of intracellular major histocompatibility complex class II (MHCII) that continuously recycles from peptide loading compartments to...